Abstract
Various aspects of epilepsy, including its evolution, were studied in 78 children with mental retardation in a prospective 5-year (1989-1994) follow-up study. Level of mental retardation was moderate or even more severe (IQ < 50) in 83\% of children, and 56\% suffered from significant cerebral palsy. Epilepsy remained uncontrolled in 28\% of cases, 2-year remission was achieved by 26\%, and mortality was 12\% during the study period. Associated cerebral palsy was the most important single risk factor for severe epilepsy, and several handicaps seemed to have a strong multiplicative effect. Complexity of epilepsy in children with mental retardation was reflected by the evolutionary features described.
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