%0 Journal Article %1 howren2024first %A Howren, Alyssa %A Sayre, Eric C %A Avina-Zubieta, J Antonio %A Puyat, Joseph H %A Da Costa, Deborah %A Xie, Hui %A Davidson, Eileen %A De Vera, Mary A %C United States %D 2024 %J Arthritis care & research %K anxiety depression health_care inflammatory_arthritis medicine %P 10.1002/acr.25294-- %R 10.1002/acr.25294 %T "What came first?" Population-based evaluation of health care encounters for depression and anxiety before and after inflammatory arthritis diagnosis: Disentangling the relationship between mental health and arthritis %U https://pubmed.ncbi.nlm.nih.gov/38191988 %X OBJECTIVE: Describe patterns of depression and anxiety health care use pre- and post-diagnosis among patients with inflammatory arthritis (IA), namely ankylosing spondylitis (AS), psoriatic arthritis (PsA), and rheumatoid arthritis (RA). METHODS: We used population-based linked administrative health data from British Columbia, Canada to build a cohort of patients (≥18 years) with incident IA and individuals without IA ('IA-free controls') matched on age and sex. We computed the proportion of IA patients and controls having ≥1 depression or ≥1 anxiety health care encounter and use of ≥1 antidepressant or ≥1 anxiolytic in each yearly interval 5-years pre- and post-IA diagnosis. We used multivariable logistic regression models to evaluate the association between IA status and aforementioned depression and anxiety health care use outcomes in each yearly interval. RESULTS: 80,238 individuals with IA (62.9% female; mean age 56.2 ±16.7 years) and 80,238 IA-free controls (62.9% female; mean age 56.2 ±16.6 years) were identified between 01/01/2001 to 03/31/2018. Individuals with IA had significantly increased odds of depression and anxiety health care encounters and dispensation of antidepressants and anxiolytics, for each yearly interval pre- and post-diagnosis. Adjusted odds ratios (aORs) were highest in the year immediately before (≥1 depression visit: aOR 1.61, 95% confidence interval CI 1.55 to 1.66; ≥1 anxiolytic: aOR 1.71, 95% CI 1.66 to 1.77) or after (≥1 antidepressant: aOR 1.95, 95% CI 1.89 to 2.00) IA diagnosis. CONCLUSION: Findings suggest a role for depression and anxiety in characterizing the IA prodrome and generate hypotheses regarding overlapping biopsychosocial processes that link IA and mental health comorbidities.

@article{howren2024first, abstract = {OBJECTIVE: Describe patterns of depression and anxiety health care use pre- and post-diagnosis among patients with inflammatory arthritis (IA), namely ankylosing spondylitis (AS), psoriatic arthritis (PsA), and rheumatoid arthritis (RA). METHODS: We used population-based linked administrative health data from British Columbia, Canada to build a cohort of patients (≥18 years) with incident IA and individuals without IA ('IA-free controls') matched on age and sex. We computed the proportion of IA patients and controls having ≥1 depression or ≥1 anxiety health care encounter and use of ≥1 antidepressant or ≥1 anxiolytic in each yearly interval 5-years pre- and post-IA diagnosis. We used multivariable logistic regression models to evaluate the association between IA status and aforementioned depression and anxiety health care use outcomes in each yearly interval. RESULTS: 80,238 individuals with IA (62.9% female; mean age 56.2 ±16.7 years) and 80,238 IA-free controls (62.9% female; mean age 56.2 ±16.6 years) were identified between 01/01/2001 to 03/31/2018. Individuals with IA had significantly increased odds of depression and anxiety health care encounters and dispensation of antidepressants and anxiolytics, for each yearly interval pre- and post-diagnosis. Adjusted odds ratios (aORs) were highest in the year immediately before (≥1 depression visit: aOR 1.61, 95% confidence interval [CI] 1.55 to 1.66; ≥1 anxiolytic: aOR 1.71, 95% CI 1.66 to 1.77) or after (≥1 antidepressant: aOR 1.95, 95% CI 1.89 to 2.00) IA diagnosis. CONCLUSION: Findings suggest a role for depression and anxiety in characterizing the IA prodrome and generate hypotheses regarding overlapping biopsychosocial processes that link IA and mental health comorbidities.}, added-at = {2024-01-14T11:23:41.000+0100}, address = {United States}, author = {Howren, Alyssa and Sayre, Eric C and Avina-Zubieta, J Antonio and Puyat, Joseph H and Da Costa, Deborah and Xie, Hui and Davidson, Eileen and De Vera, Mary A}, biburl = {https://www.bibsonomy.org/bibtex/2b30158a23979d9d691072c43ddda7e65/tabularii}, comment = {38191988[pmid]}, description = {"What came first?" Population-based evaluation of health care encounters for depression and anxiety before and after inflammatory arthritis diagnosis: Disentangling the relationship between mental health and arthritis - PubMed}, doi = {10.1002/acr.25294}, interhash = {daa87b3b363cac7fa77147416006a056}, intrahash = {b30158a23979d9d691072c43ddda7e65}, issn = {21514658}, journal = {Arthritis care & research}, keywords = {anxiety depression health_care inflammatory_arthritis medicine}, month = jan, pages = {10.1002/acr.25294--}, timestamp = {2024-01-14T11:23:41.000+0100}, title = {"What came first?" Population-based evaluation of health care encounters for depression and anxiety before and after inflammatory arthritis diagnosis: Disentangling the relationship between mental health and arthritis}, url = {https://pubmed.ncbi.nlm.nih.gov/38191988}, year = 2024 }