Ampakines capable of improving cognition by enhancing brain activity under normal circumstances may also have the potential to reduce the harmful or unwanted effects of sleep deprivation. (CX717 by Cortex Pharmaceuticals)
Armodafinil (Nuvigil®) is an eugeroic drug made by Cephalon, FDA-approved 6/15/2007. Clinical trials for its use in bipolar disorder, cognition in schizophrenia, excessive fatigue in Parkinson's & cancer, begin. Patent expires 2023.
Armodafinil From Wikipedia, the free encyclopedia Jump to: navigation, search Armodafinil Systematic (IUPAC) name (-)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide Identifiers CAS number 68693-11-8 ATC code N06BA07 PubChem ? Chemical data Formu
Full-text, online textbook discussing various pharmaceutical, neutraceutical, and lifestyle interventions for enhancing life by facilitating our efforts to reach our fullest potential.
Modafinil induces wakefulness, but its dopamine-releasing action in the nucleus accumbens is weak and dose-dependent; no likelihood of euphoric response ('abuse potential').
Unlike conventional stimulants, no anxiety, agitation and insomnia; selectively stimulates brain's adrenergic receptors for norepinephrine (noradrenaline), a neurotransmitter linked to alertness, learning, and memory.
Accounts of use for depression, ADD/ADHD, fibromyalgia, chronic fatigue (off-label). Metabolic precursor to modafinil; takes 1 hr to kick in, hard on liver. Not "controlled" like modafinil/Provigil.
J Clin Psychiatry 2000 May;61(5):378-81 Modafinil augmentation of antidepressant treatment in depression. Menza MA, Kaufman KR, Castellanos A Department of Psychiatry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical Sch