Ampakines capable of improving cognition by enhancing brain activity under normal circumstances may also have the potential to reduce the harmful or unwanted effects of sleep deprivation. (CX717 by Cortex Pharmaceuticals)
Super eugeroic 'armodafinil' (Nuvigil), by modafinil’s creator, Cephalon, is FDA-approved. Ampakine CX717 from Cortex is in clinical trials. Both drugs promise even longer periods of wakefulness.