This study adds epidemiological weight to the implementation of health maintenance strategies and risk management procedures to reduce the risk of violent outcomes in individuals with mental health disorders (specifically, substance use disorder, psychosis, and ‘personality disorders’). The findings highlight how experiences of victimisation and perpetration are more often comorbid, with experiences of both victimisation and perpetration more common than an experience of only one of the outcomes.
This editorial presents ten principles for the design and development of effective psychological treatments for psychosis. Open access article - no login required.
This study uses habit formation models to investigate the dynamic interplay between psychosis, clozapine dose and obsessive–compulsive symptoms (OCS). Open access article - no login required.
This study found higher ethnic density related to lower risk of FEP within the Pakistani population in East Lancashire, highlighting the impact of local social context on psychosis incidence. Open access article - no login required.
This study aimed to investigate the relationship between cytokines levels, clinical symptoms and cognitive impairments in CR-TRS patients, both with and without MetS. Open access article - no login required
The aim of the present study was to evaluate the associations of OS parameters with psychopathological symptoms in male chronically medicated schizophrenia (CMS) and treatment-resistant schizophrenia (TRS) patients. Open access article - no login required
this study contributes to the growing evidence-base which suggests that ACT could be another treatment option for people with psychosis. Further studies of ACT for people with psychosis are required to continue building upon the evidence-base.
Within healthcare services, we facilitate ACT-based groups for people with mental health difficulties. We have an opportunity here to set up ACT-based groups specifically for people with psychosis and conduct service evaluation studies to evaluate their feasibility in services.
"I believe this study has one major implication for clinical practice – it highlights the urgent need to improve the survival rates of patients with psychosis.
It is unacceptable that 13-14% of people with a FEP in this study passed away by the 20-year follow-up, especially given the average age for these patients was just 46. This rate is likely to be the result of multiple factors, including death by suicide (3.5%). We know that the main cause of death in these patients is cardiovascular-related, and more research is needed to investigate why this is the case, and what to do about it."
Based on a number needed to assess (NNA) of 18 for clinically relevant abnormalities, Blackman et al. (2023) conclude that their findings “support the use of MRI as part of the initial clinical assessment of all patients with FEP.” However, due to the authors’ liberal definition of clinical relevance together with the exclusion of patients with a suspected non-psychiatric cause of psychosis in most of the included studies, it remains debatable whether routine screening is warranted for all patients with FEP. Given recent evidence about the prevalence of autoimmune encephalitis as a potential cause of FEP (Scott et al., 2018), there may be other diagnostic procedures that are better warranted than routine neuroimaging in FEP depending on clinical presentation.
This study is important because it raises awareness of available resources, such as HVGs and peer support, from which people who hear voices can access care outside mental health services. The findings can be used to inform further training for professionals working in secondary care mental health services (i.e., CMHTs) and/or those supporting people who hear voices. Healthcare professionals should be aware of the benefits of HVGs and other groups and encourage collaborations between HVGs and the NHS (i.e., via signposting or community referrals).
This study evaluated the relationship between negative symptoms, daily time use (productive/non-productive activities, PA/NPA), and negative emotions in schizophrenia-spectrum disorders (SSDs): 618 individuals with SSDs (311 residential care patients [RCPs], 307 outpatients) were surveyed about socio-demographic, clinical (BPRS, BNSS) and daily time use (paper-and-pencil Time Use Survey completed twice/week) characteristics.
This systematic review aimed to review neuroimaging studies comparing clozapine-resistant schizophrenia patients with clozapine-responding patients, and with first-line antipsychotic responding (FLR) patients.
Vitamin D deficiency is prevalent in people with established psychotic disorders, but less is known about vitamin D levels in people with first-episode psychosis (FEP). This study aimed to determine the prevalence of vitamin D deficiency in people with FEP and identify the factors associated with vitamin D status.
The quality of life in people with psychosis has been consistently demonstrated to be lower than those without, with self-stigma contributing greatly to this impairment. Hence, it is imperative to address this gap in order to facilitate recovery-oriented and other outcomes. This study investigates the potential of religiosity in moderating the effects of self-stigma on quality of life among those with psychosis. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Schizophrenia is associated with increased risk of cardiovascular disease (CVD), although there is variation in risk among individuals. There are indications of shared genetic etiology between schizophrenia and CVD, but the nature of the overlap remains unclear. The aim of this study was to fill this gap in knowledge. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Identification of robust biomarkers that predict individualized response to antipsychotic treatment at the early stage of psychotic disorders remains a challenge in precision psychiatry. The aim of this study was to investigate whether any functional connectome-based neural traits could serve as such a biomarker. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Culture has been posited to be involved in the formation and maintenance of delusions and hallucinations. The extent of these differences and how they affect explanatory models of psychosis and help-seeking attitudes remains to be understood. This review aims to present a cultural formulation to account for psychosis onset, symptom maintenance, and help-seeking attitudes.
A. Laenen, T. Vangeneugden, H. Geys, и G. Molenberghs. The British journal of mathematical and statistical psychology, 59 (Pt 1):
113-31(мая 2006)Mesures de concordància; Online; ICC; Psiquiatria.