A single protein in the brain influences arousal of despair, according to new study in mice. Brain biopsies revealed that mice trying hardest to escape shocks had highest levels of delta-FosB - which may also help humans avoid hopelessness & helplessness.
Modafinil induces wakefulness, but its dopamine-releasing action in the nucleus accumbens is weak and dose-dependent; no likelihood of euphoric response ('abuse potential').
Weak willpower & procrastination caused by dopamine hypofunction is one of those neurological deficiencies which effort alone can't overcome. Happily, in our transhuman paradise, even the most lethargic spirit can move mountains.
Authorities report that more than half the population experiences trauma, which makes people more likely to develop PTSD, depression, anxiety and physical illness later in life. Now, a new study finds that among ‘healthy’ individuals, those who displa
The social avoidance that normally develops when a mouse repeatedly experiences defeat by a dominant animal disappears when it lacks a gene for a memory molecule in a brain circuit for social learning, scientists funded by the National Institutes of Healt
PTSD, coping ability, positive outlook, proactive behavior, ability to evoke gratitude for what IS working, sense of hopefulness and efficacy, in women...
Unlike conventional stimulants, no anxiety, agitation and insomnia; selectively stimulates brain's adrenergic receptors for norepinephrine (noradrenaline), a neurotransmitter linked to alertness, learning, and memory.
Here's just one: Even talking about posthuman psychological superhealth is morally frivolous. Another? Promoting superhappiness may lead to what one may call, informally, "inappropriate" behavioural responses.
depressed individuals actually have more realistic perceptions of their own image, importance, and abilities than the average person. While it’s still generally accepted that depressed people can be negatively biased in their interpretation of events an