The underlying patho-physiology of asthma, regardless of allergic components or triggering mechanisms, is airway inflammation. At the center of this improper inflammatory reaction is the T-cell. There is increasing evidence that the underlying process dri
The novel neuropeptides hypocretin and orexin, located recently on the lateral hypothalamic cells, has been linked to both feeding and sleeping/waking cycles. Recent studies have found an association between defects in hypocretin/orexin and narcolepsy.