Interpersonal psychotherapy for adolescents (IPT‐A) is a manualised, time‐limited intervention for young people with depression. This systematic review aimed to determine the effectiveness of IPT‐A for treating adolescent depression.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Anxiety runs in families, and its transmission is largely environmental. However, studies rarely explore this process in clinically anxious parents or ask participants to face a genuine fear. We also do not know whether this process is modifiable. This study will explore these questions using a sample of clinically anxious parents.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
In this Review, we assess this evidence in relation to rheumatoid arthritis and depression, with a focus on innate immune and molecular responses to inflammation, and discuss the challenges of assessing causation in this population, acknowledging the difficulty of assessing the confounding and contributory effects of pain and fatigue. We also discuss how future clinical and preclinical research might improve diagnosis of depression in people with rheumatoid arthritis and shed light on mechanisms that could be substrates for therapeutic interventions.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Reports in the UK media were broadly accurate and balanced, although the headlines didn't make it clear that the study was carried out in mice, not humans.
Letter. In their meta‐analysis, Kohler‐Forsberg and colleagues (1) analyzed the efficacy or rather effect of anti‐inflammatory treatment on major depressive disorder or depressive symptoms. In the discussion of limitations of their meta‐analysis, they briefly mention that “although the antidepressant effects of NSAIDs have been shown to be independent of their pain‐relieving effects, the antidepressant effect of anti‐inflammatory agents may be mediated via their effect on somatic diseases.”..... To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
There is good evidence that job stressors are prospectively related to mental health problems, particularly depressive symptoms. This review aimed to examine whether job stressors were also related to use of psychotropic medications. To read the full article, log in using your MPFT NHS OpenAthens details.
Open access. Depression is usually managed in primary care, but most antidepressant trials are of patients from secondary care mental health services, with eligibility criteria based on diagnosis and severity of depressive symptoms. Antidepressants are now used in a much wider group of people than in previous regulatory trials. We investigated the clinical effectiveness of sertraline in patients in primary care with depressive symptoms ranging from mild to severe and tested the role of severity and duration in treatment response..
Conclusions
Suicidal risks were high in mood disorders: ideation was highest with BD type II, attempts and suicides (especially violent) with BD type I. Several risk factors for suicidal acts differed between BD versus MDD patients.. To read the full article, log in using your MPFT NHS OpenAthens details.
A review investigating dependence and withdrawal issues associated with five commonly prescribed medicines in England has been published by PHE (2019), covering the latest evidence and highlighting patients& experiences.
The findings indicate that antidepressants in particular are being prescribed in much greater numbers and for longer durations, whereas prescriptions of benzodiazepines and opioids have fallen in recent years (PHE, 2019). To read the full article, log in using your MPFT NHS OpenAthens details.
To examine the incidence of suicidal and violent behaviour following initiation of antidepressant medication.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Douglas Badenoch on a meta-analysis of follow-up data from clinical trials of antidepressants, which found a small but significant increase in suicide risk.
Psychological Medicine; Cambridge Vol. 49, Iss. 13, (Oct 2019): 2168-2176. DOI:10.1017/S0033291718002994
Background
It has been proposed that vascular disease is the mechanism linking depression and cognition, but prospective studies have not supported this hypothesis. This study aims to investigate the inter-relationships between depressive symptoms, cognition and cerebrovascular disease using a well-characterised prospective cohort.. To read the full article, log in using your MPFT NHS OpenAthens details.
Psychological Medicine; Cambridge Vol. 49, Iss. 13, (Oct 2019): 2118-2133. DOI:10.1017/S0033291719001600
To what extent meditation techniques (which incorporate practices to regulate attention, construct individual values, or deconstruct self-related assumptions), are more or less effective than relaxation therapy in the treatment of anxiety, is not clear. The aim of this study was to examine the effectiveness of meditation compared to relaxation in reducing anxiety. A systematic review from PubMed, Embase, PsycInfo and the Cochrane Central was conducted.. To read the full article, log in using your MPFT NHS OpenAthens details.
Depression is a major contributor to disability across the lifespan. As a disorder that commonly has its onset in adolescence and early adulthood, and high recurrence and persistence, it is a prime candidate for early intervention. Most of the early intervention focus, however, has been confined to indicated prevention efforts. In this Personal View, we argue that early intervention for depression must expand beyond this narrow focus to include young people (aged 12–25 years old) who present with early episodes of full-threshold major depressive disorder. We discuss the development of enhanced primary care services for youth mental health, which allow young people improved access to evidence-based care. We argue that young people with severe and complex depression require particular attention: they are at high risk of lifelong disabling illness and need support to alleviate the early effects of their illnesses on their functional trajectories.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Open access. Treatment of depression in cardiac patients is difficult. Patients’ illness beliefs regarding depression are associated with outcomes. The aim of the mixed-methods study was to test whether patients in routine care for depression differ from patients with depression in routine care for cardiac diseases regarding illness beliefs about depression.
Open access.Women are more susceptible to major depressive disorder (MDD). A possible explanation is that women have a trait tendency to engage in a ruminative response style. Depending on cognitive model of depression, attention bias, memory bias and self-referential bias were closely related among depressed patients. Previous studies have explored the neural mechanism of the cognitive biases by using amplitude of low frequency fluctuations (ALFF) or functional connectivity (FC), and few combined these two metrics, especially focusing on female patients.
Open access. Seasonal affective disorder (SAD) is a seasonally recurrent type of major depression that has detrimental effects on patients’ lives during winter. Little is known about how it affects patients during summer and about patients’ and physicians’ perspectives on preventive SAD treatment. The aim of our study was to explore how SAD patients experience summers, what type of preventive treatment patients implement, which preventive treatment methods, if any, physicians recommend, and what factors facilitate or hinder implementation/recommendation of SAD prevention.
To examine longitudinally risk factors for suicide in depression, and gender differences in risk factors and suicide methods.. To read the full article, log in using your MPFT NHS OpenAthens details.
To evaluate the effects of depressive symptom management interventions for low‐income mothers.. To read the full article, log in using your MPFT NHS OpenAthens details.
In this systematic review and meta‐analysis, the response, remission, and speed of response in adults with major depressive disorder (MDD) and bipolar disorder in depressive episode (BDD) receiving an acute course of electroconvulsive therapy (ECT) were quantitatively analyzed.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.