Many people are interested in using marijuana for therapeutic purposes as legalization expands across the country (USA). The impact of marijuana depends upon the consumed potency and dose of its major psychoactive components, tetrahydrocannabinol and cannabidiol, which have very different psychiatric effects. This Open Forum discusses what is known about the impact of these marijuana constituents on people with serious mental illnesses, who may experience many adverse effects and more easily develop addiction with marijuana use. As use of medical marijuana increases, mental health clinicians can help prevent or address adverse effects by informing themselves and others about marijuana’s effects and by coordinating with marijuana prescribers.. Login at top right hand side of page using your MPFT NHS OpenAthens for full text.
Open access. Off-label ketamine treatment has shown acute antidepressant effects that offer hope for patients with therapy-resistant depression. However, its potential for integration into treatment algorithms is controversial, not least because the evidence base for maintenance treatment with repeated ketamine administration is currently weak. Ketamine is also a drug of misuse, which has raised concerns regarding the target population. Little is known about which patients would seek ketamine treatment if it were more widely available.
Aims. To explore some of the characteristics of the patients actively seeking ketamine treatment.
There is limited evidence on what shapes Amphetamine Type Stimulant (ATS) use trajectories. This systematic narrative review and qualitative synthesis aimed to identify individual, social and environmental influences shaping key phases in the ATS use trajectory: initiation, continuation, increase/relapse, and decrease/abstinence.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Psychology of Addictive Behaviors (Aug 30, 2018). DOI:10.1037/adb0000381
Abstinence from alcohol is often considered a critical element of recovery from alcohol use disorder. Yet, low risk drinking may be more desirable for some patients. There is mixed literature on whether low risk drinking is achievable and stable. Low risk drinking outcomes during treatment and outcomes 3 years after treatment were examined using data from the outpatient arm in Project MATCH (n = 877). . To read the full article, log in using your NHS OpenAthens details.
Current medications for alcohol use disorder do not target brain noradrenergic pathways. Theoretical and preclinical evidence suggests that noradrenergic circuits may be involved in alcohol reinforcement and relapse. After a positive pilot study, the authors tested the α-1 adrenergic receptor antagonist prazosin to treat alcohol use disorder in a larger sample.. To read the full article, log in using your MPFT NHS OpenAthens details.
Exposure to child maltreatment has been shown to increase lifetime risk for substance use disorders (SUD). However, this has not been systematically examined among race/ethnic groups, for whom rates of exposure to assaultive violence and SUD differ. This study examined variation by race/ethnicity and gender in associations of alcohol (AUD), cannabis (CUD), and tobacco (TUD) use disorders with three types of childhood interpersonal violence (cIPV): physical abuse, sexual abuse, and witnessing parental violence. To read the full article, log in using your NHS OpenAthens details.
Journal of Consulting and Clinical Psychology Vol. 86, Iss. 9, (Sep 2018): 765-774. DOI:10.1037/ccp0000323
Objective: Drinking goals set at treatment onset predict treatment outcome in patients with alcohol use disorders. Yet the cognitive constructs of goal setting and goal attainment are understudied in young adult drinkers. This study sought to examine how the interplay of goal setting and goal attainment during treatment impacts treatment outcome in a sample of young adult heavy drinkers. . To read the full article, log in using your NHS OpenAthens details.
Expanded access to naloxone has been identified as a key intervention for reducing opioid related morbidity and mortality. It is not known which naloxone device will result in rapid, successful administration when administered by community members. The aims of this study were to estimate and compare 1) the rate of successful administration and 2) time to successful administration for single step nasal spray, multi‐step atomized nasal spray, and intramuscular simulated naloxone by community members.
Excessive alcohol consumption has a substantial impact on public health services. A key element determining alcohol availability is alcohol outlet density. This study investigated the relationship between on‐trade and off‐trade outlets and hospital admission rates in local neighbourhoods.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
The U.S. National Institutes of Mental Health Research Domain Criteria (RDoC) seek to stimulate research into biologically validated neuropsychological dimensions across mental illness symptoms and diagnoses. The RDoC framework comprises 39 functional constructs designed to be revised and refined, with the overall goal to improve diagnostic validity and treatments. This study aimed to reach a consensus among experts in the addiction field on the ‘primary' RDoC constructs most relevant to substance and behavioural addictions.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
To understand the extent of the alcohol industry's financial dependence on drinking above government low‐risk guidelines in England.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Studies examining the next‐day cognitive effects of heavy alcohol consumption have produced mixed findings, which may reflect inconsistencies in definitions of ‘hangover’. Recent consensus has defined hangover as “mental and physical symptoms, experienced the day after a single episode of heavy drinking, starting when blood alcohol concentration (BAC) approaches zero”. In light of this, we aimed to review the literature systematically to evaluate and estimate mean effect sizes of the next‐day effects of heavy alcohol consumption on cognition.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
The emergence of negative affective symptoms over the course of alcohol use disorders (AUDs) (e.g. “dark side symptoms”) has been suggested theoretically,; however, the description of their occurrence is limited. This study operationalized two negative affect symptoms and tested the strength of association between these phenotypes and 1) indicators of the clinical course of the severity of AUD, 2) comorbid Axis I psychiatric disorders, suicidal behaviors, and trait neuroticism, and 3) whether participants reported drinking to relieve the negative affective symptoms.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
An expert in substance abuse reacts to a new study published in the Lancet that suggests there is no safe level of alcohol consumption for the one in three people who drink alcohol worldwide.
Veterans with mental health problems are a high-risk group for substance misuse difficulties and are over-represented in forensic settings. Yet, there are few substance misuse services available for this population. Evidence suggests that case management can provide effective interventions for veterans with substance misuse problems. However, there is little research to show its effectiveness in the UK. The present study reported on the implementation and preliminary outcomes of the Veterans Forensic Substance Misuses Service (VFSMS), piloted within a prison setting, to demonstrate the feasibility of the service.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai