Abstract
porB DNA sequence analysis and Neisseria gonorrhoeae multiantigen sequence typing (NG-MAST) methods were compared for their abilities to discriminate strains and to identify epidemiologically congruent pairs of N. gonorrhoeae. Both methods provided high-level discrimination of strains. NG-MAST further differentiated large porB-based clusters. However, considerations of cost suggest that porB DNA sequence analysis is a useful tool for preliminary molecular analysis of the epidemiology of N. gonorrhoeae.
- analysis
- analysis,
- antigens,
- bacterial
- bacterial,
- cluster
- data,
- epidemiology,
- female,
- genotype,
- gonorrhea,
- gonorrhoeae,
- humans,
- male,
- molecular
- molecular,
- neisseria
- porins,
- sequence
- techniques,
- typing
- {dna,}
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