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No evidence that extended tracts of homozygosity are associated with Alzheimer's disease.

R. Sims, S. Dwyer, D. Harold, A. Gerrish, P. Hollingworth, J. Chapman, N. Jones, R. Abraham, D. Ivanov, J. Pahwa, V. Moskvina, K. Dowzell, C. Thomas, A. Stretton, S. Lovestone, J. Powell, P. Proitsi, M. Lupton, C. Brayne, D. Rubinsztein, M. Gill, B. Lawlor, A. Lynch, K. Morgan, K. Brown, P. Passmore, D. Craig, B. McGuiness, S. Todd, J. Johnston, C. Holmes, D. Mann, A. Smith, S. Love, P. Kehoe, J. Hardy, S. Mead, N. Fox, M. Rossor, J. Collinge, G. Livingston, N. Bass, H. Gurling, A. McQuillin, L. Jones, P. Holmans, M. O'Donovan, M. Owen, и J. Williams. Am J Med Genet B Neuropsychiatr Genet, 156B (7): 764--771 (декабря 2011)
DOI: 10.1002/ajmg.b.31216

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's diseaseD. Harold, R. Abraham, P. Hollingworth, R. Sims, A. Gerrish, M. Hamshere, J. Pahwa, V. Moskvina, K. Dowzell, A. Williams и 76 other автор(ы). NAT GENET, 41 (10): 1088--U61 (октября 2009)Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.P. Hollingworth, D. Harold, R. Sims, A. Gerrish, J. Lambert, M. Carrasquillo, R. Abraham, M. Hamshere, J. Pahwa, V. Moskvina и 165 other автор(ы). Nat Genet, 43 (5): 429--435 (мая 2011)PMCID: PMC3084173.Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's diseaseD. Harold, R. Abraham, P. Hollingworth, R. Sims, A. Gerrish, M. Hamshere, J. Pahwa, V. Moskvina, K. Dowzell, A. Williams и 76 other автор(ы). Nature Genetics, 41 (10): 1088--1093 (2009)Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's diseaseP. Hollingworth, D. Harold, R. Sims, A. Gerrish, J. Lambert, M. Carrasquillo, R. Abraham, M. Hamshere, J. Pahwa, V. Moskvina и 162 other автор(ы). Nature Genetics, 43 (5): 429--436 (2011)Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's diseaseL. Jones, P. Holmans, M. Hamshere, D. Harold, V. Moskvina, D. Ivanov, A. Pocklington, R. Abraham, P. Hollingworth, R. Sims и 72 other автор(ы). PLoS ONE, (2010)Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.L. Jones, P. Holmans, M. Hamshere, D. Harold, V. Moskvina, D. Ivanov, A. Pocklington, R. Abraham, P. Hollingworth, R. Sims и 74 other автор(ы). PLoS One, 5 (11): e13950 (2010)PMCID: PMC2981526.The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's diseaseA. Gerrish, G. Russo, A. Richards, V. Moskvina, D. Ivanov, D. Harold, R. Sims, R. Abraham, P. Hollingworth, J. Chapman и 83 other автор(ы). Journal of Alzheimer's Disease, 28 (2): 377--387 (2012)No evidence that extended tracts of homozygosity are associated with Alzheimer's disease.R. Sims, S. Dwyer, D. Harold, A. Gerrish, P. Hollingworth, J. Chapman, N. Jones, R. Abraham, D. Ivanov, J. Pahwa и 39 other автор(ы). Am J Med Genet B Neuropsychiatr Genet, 156B (7): 764--771 (декабря 2011)

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