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Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor

, , , , , и . Symp Soc Exp Biol, (1990)Hausdorff, W P Lohse, M J Bouvier, M Liggett, S B Caron, M G Lefkowitz, R J 1F32GM13182/GM/NIGMS NIH HHS/United States HL02386/HL/NHLBI NIH HHS/United States HL16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. England Symposia of the Society for Experimental Biology Symp Soc Exp Biol. 1990;44:225-40..

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Structure and regulation of G protein-coupled receptors: the beta 2-adrenergic receptor as a model, , , , и . Vitam Horm, (1991)Collins, S Lohse, M J O'Dowd, B Caron, M G Lefkowitz, R J Review United states Vitamins and hormones Vitam Horm. 1991;46:1-39..Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase, , , , и . Proc Natl Acad Sci U S A, 88 (14): 6201-4 (июля 1991)Roth, N S Campbell, P T Caron, M G Lefkowitz, R J Lohse, M J HL16037/HL/NHLBI NIH HHS/United States Comparative Study Research Support, U.S. Gov't, P.H.S. United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6201-4..Inhibition of beta-adrenergic receptor kinase prevents rapid homologous desensitization of beta 2-adrenergic receptors, , , и . Proc Natl Acad Sci U S A, 86 (9): 3011-5 (мая 1989)Lohse, M J Lefkowitz, R J Caron, M G Benovic, J L Comparative Study Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1989 May;86(9):3011-5..Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors, , , , , , и . J Biol Chem, 268 (5): 3201-8 (февраля 1993)Pippig, S Andexinger, S Daniel, K Puzicha, M Caron, M G Lefkowitz, R J Lohse, M J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1993 Feb 15;268(5):3201-8..Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase, , , , , , и . Br J Clin Pharmacol, (1990)Benovic, J L Onorato, J Lohse, M J Dohlman, H G Staniszewski, C Caron, M G Lefkowitz, R J England British journal of clinical pharmacology Br J Clin Pharmacol. 1990;30 Suppl 1:3S-12S..Cloning, expression, and chromosomal localization of beta-adrenergic receptor kinase 2. A new member of the receptor kinase family, , , , , , , , , и . J Biol Chem, 266 (23): 14939-46 (августа 1991)Benovic, J L Onorato, J J Arriza, J L Stone, W C Lohse, M Jenkins, N A Gilbert, D J Copeland, N G Caron, M G Lefkowitz, R J GM44944/GM/NIGMS NIH HHS/United States HL16037/HL/NHLBI NIH HHS/United States N01-CO-74101/CO/NCI NIH HHS/United States Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 1991 Aug 15;266(23):14939-46..Phosducin, potential role in modulation of olfactory signaling, , , , , , и . J Biol Chem, 272 (7): 4606-12 (февраля 1997)Boekhoff, I Touhara, K Danner, S Inglese, J Lohse, M J Breer, H Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United states The Journal of biological chemistry J Biol Chem. 1997 Feb 14;272(7):4606-12..Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors, , , и . J Biol Chem, 265 (6): 3202-11 (февраля 1990)Lohse, M J Benovic, J L Caron, M G Lefkowitz, R J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1990 Feb 25;265(6):3202-11..Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor, , , , , и . Symp Soc Exp Biol, (1990)Hausdorff, W P Lohse, M J Bouvier, M Liggett, S B Caron, M G Lefkowitz, R J 1F32GM13182/GM/NIGMS NIH HHS/United States HL02386/HL/NHLBI NIH HHS/United States HL16037/HL/NHLBI NIH HHS/United States Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. England Symposia of the Society for Experimental Biology Symp Soc Exp Biol. 1990;44:225-40..The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor, , , , , и . Nature, 335 (6188): 358-60 (сентября 1988)Fargin, A Raymond, J R Lohse, M J Kobilka, B K Caron, M G Lefkowitz, R J Research Support, Non-U.S. Gov't England Nature Nature. 1988 Sep 22;335(6188):358-60..