Exposure to secondhand smoke leads to inflammation and oxidation, representing another pathophysiologic mechanism for the development of atherosclerosis.
Researchers say circulating mononuclear cells (the largest type of white blood cell) and lymphocytes, exist in a proinflammatory state in obese persons known to be at increased risk of developing heart disease, diabetes, or both.
Accumulating evidence supports the hypothesis that chronic low-grade inflammation and activation of the innate immune system are closely involved in the pathogenesis of the type 2 diabetes.
In conclusion, the daily supplementary intake of 500 mg green tea polyphenols did not have clear effects on blood glucose level, Hb Alc level, insulin resistance or inflammation markers. The positive correlation between the level of polyphenol intake and
The cellular and extracellular matrix accumulations that comprise the lesions of atherosclerosis are driven by local release of cytokines at sites of predilection for lesion formation, and by the specific attraction and activation of cells expressing rece
it may no longer be enough to measure just HDL levels without determining levels of paroxonase and platelet-activating acetylhydrolase; levels of these enzymes may determine whether HDL is proinflammatory or protective. Likewise, measuring Lp(a) and small
For "traditional" cardiologists, CAD is a blockage or blockages in the coronary arteries, and the treatment is stents. For "nontraditional" cardiologists, CAD is a more systemic, diffuse condition, and the treatment is systemic.
Journal of Nutrition, Vol 128 No 2 February 1998 Muredach P Reilly, John A Lawson, and Garret A FitzGerald Center for Experimental Therapeutics, University of Pennsylvania School of Medicine Philadelphia, PA 19104
The same cytokine may have different effects in different circumstances. (This is called ' pleotropy '). See below chart for key functions of significant cytokines.
Although in many cases the cause of anemia is not found, a primary deficiency of erythropoietin may be at fault in at least some of these cases since the response of erythropoietin to anemia may decrease in individuals over age 70. Conclusions: Anemia sh
Chronic inflammation appears to contribute to tumor progression by establishing a milieu conducive to development of different cancers at all three stages of tumor development: initiation, progression and metastasis, inducing the release of a variety of c
Evidence emerged from studies in mice that hepcidin, a small peptide hormone exclusively produced in the liver in response to inflammation, could completely or nearly completely shut down normal iron hemostasis.