Aging may be an intrinsic factor in the development of anemia, possibly through the age-related dysregulation of certain proinflammatory cytokines such as interleukin-6 (IL-6)...Increased IL-6 and other proinflammatory cytokines directly inhibit erythropo
Although in many cases the cause of anemia is not found, a primary deficiency of erythropoietin may be at fault in at least some of these cases since the response of erythropoietin to anemia may decrease in individuals over age 70. Conclusions: Anemia sh
Adjusting for confounders, we found that total and bioavailable testosterone levels were associated with hemoglobin levels in women and in men. Conclusion Older men and women with low testosterone levels have a higher risk of anemia.
Hypotheses for chronic anemia in the elderly: (1) sarcopenia, with decrease in muscle mass triggering decreased red blood cell mass, oxygen utilization, and erythropoietin production; (2) declining stem cell clones related to hematopoiesis or altered stem
Research on chronic inflammation and its role in geriatric, chronic anemia; dyregulation of inflammatory cytokines is correlated with anemia of chronic disease...