In the Injury Theory, it's damage to the arterial endothelium, followed by platelet activation, then smooth muscle cell migration to injury, then macrophages, with resulting "foam cells." Engorged foam cells burst, starting the injury cycle all over again
Vermont officials said drug company payments to psychiatrists in the state averaged $45,692 EACH!, up from $20,835 in 2005; this doesn't include drug samples...
After participating in this activity, participants should be better able to: Review the epidemiology and pathogenesis of acute bronchitis, including a discussion of the bacteriologic etiology. Discuss clinical features that are diagnostic of acute bro
The morbidity, mortality, expense and transient benefits of a high technology approach toward the coronary disease epidemic, has failed. It is time to realize that the answer to a faulty lifestyle epidemic is not drugs and technology – it is lifestyle.
RxNorm, a standardized nomenclature for clinical drugs, is produced by the National Library of Medicine (NLM). In this context, a clinical drug is a pharmaceutical product given to (or taken by) a patient with a therapeutic or diagnostic intent. In RxNorm
xNav is a browser for RxNorm, the NLM repository of standard names for clinical drugs. RxNav displays links from clinical drugs, both branded and generic, to their active ingredients, drug components and related brand names. RxNorm is one of a suite of de
"Pharma 2020: The Vision - Which Path Will You Take? indicates that the current pharmaceutical industry business model is both economically unsustainable and operationally incapable of acting quickly enough"
Our patient exemplified the challenges involved in a CTO, which included the length of the lesion, the lack of a proximal nipple, the presence of a side branch at the occlusion point, poor visualization of the distal vessel despite contralateral injection
There are thousands of promising drugs for treating diseases that are simply not getting studied or brought to market because they are derived from natural or common substances that can't be patented. The dirty little secret of the pharma business is that
For "traditional" cardiologists, CAD is a blockage or blockages in the coronary arteries, and the treatment is stents. For "nontraditional" cardiologists, CAD is a more systemic, diffuse condition, and the treatment is systemic.
Ketamine blocks a brain protein called the N-methyl-D-aspartic acid (NMDA) receptor. Previous studies have shown that agents that block the NMDA receptor reduce depression-like behaviors in animals.
Dichloroacetate (DCA) committs "immortal" cancer cells to a natural death while leaving normal cells unharmed - but DCA is not patentable, so pharmaceutical companies have no incentive to begin clinical trials...