A relationship exists between cytokines and both leptin (L4146) and insulin ( I1507). Proinflammatory cytokines increase leptin levels while leptin regulates pro- and anti-inflammatory cytokine production.
The cellular and extracellular matrix accumulations that comprise the lesions of atherosclerosis are driven by local release of cytokines at sites of predilection for lesion formation, and by the specific attraction and activation of cells expressing rece