German drugmaker Boehringer Ingelheim didn't set out to create a Viagra-like drug for women. The company was simply trying to develop a fast-acting antidepressant, one that patients would respond to in a matter of days, not weeks as in most current treatm
In patients with depression who experience sedation as a side effect of antidepressants, adjunctive modafinil improved wakefulness & reduced fatigue. Modafinil plus SSRIs improved mood & quality of life.
J Clin Psychiatry 2000 May;61(5):378-81 Modafinil augmentation of antidepressant treatment in depression. Menza MA, Kaufman KR, Castellanos A Department of Psychiatry, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical Sch
Rapidly restores vigilance and alertness in older people and the physically and mentally tired. Has a powerful antidepressant action far superior to that of fluoxetine (Prozac) and clomipramine (Anafranil) and is without any serious side effects. Adrafin
The effect of Adrafinil, unlike conventional stimulants, builds subtly over a period of days to months. This appears to be based on its ability to selectively stimulate adrenergic receptors in the brain. These receptors normally respond to norepinephrine