This cross-sectional study aims to systematically assess and compare parenting stress in families of children with various types of disabilities. Open access article - no login required
The primary goal of this study was to examine the feasibility and effectiveness of incorporating habit training into an app-based meditation intervention to maintain reductions in depressive symptoms among autistic adults. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The study reinforces findings from the existing literature that, in the context of comorbid anxiety and depression, anxiety seems to have an earlier age of onset. Early identification and intervention for anxiety disorders may therefore help to prevent the developmental of other comorbid psychiatric disorders, such as depression or additional anxiety disorders.
By investigating parents’ depression and how it can be associated with children’s emotional difficulties, this study showed that if untreated, mental ill-health can have significant long-lasting effects on the mother, father and children.
As this study points out, the activating and associating depressive symptoms between family members can be targeted for more rapid recovery, and may be key to identifying who might be more at risk of developing depression in young children, and later unintentionally influencing the transmission of depression.
Overall, this research brings to light many ways in which access can be improved. However, as the authors mention, it is important to keep in mind that the process of improving access is not a “one size fits all” approach. Instead, programs that aim to improve access should carefully consider their target audience and combine a variety of complementary strategies. In conclusion, the authors talk about practice guidelines. They suggest that each category of healthcare providers would benefit from specific guidelines on improving access to CBT through their specific roles.
Childhood emotional maltreatment (CEM) is a risk factor for the pathogenesis of depressive disorders. However, it is not clear whether CEM is more strongly related to specific symptoms of depression and whether specific traits or cognitive states may mediate the association between CEM and depressive symptoms. In our cross-sectional study, including 72 patients with a current depressive episode, we investigated if CEM is specifically related to cognitive symptoms of depression.
Previously improving UK mortality trends stalled around 2012, with evidence implicating economic policy as the cause. This paper examines whether trends in psychological distress across three population surveys show similar trends. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Despite limitations, the findings from this study have important clinical and research implications for treating adolescent depression.
For clinicians, it may be beneficial at the beginning of a case of treatment for adolescent depression to develop a set of personalised outcome goals with the patient, with recognition that this is likely to vary greatly between individuals. Treatment could then be jointly chosen by the patient and clinician to ensure these priorities are addressed. This approach could also take into account what the patient thinks their key problem areas are, and what they consider to be valuable improvements. This would also provide a good framework when reviewing clinical decisions of whether to continue or change treatments.
Mother and father depression symptoms often co-occur, and together can have a substantial impact on child emotional well-being. Little is understood about symptom-level mechanisms underlying the co-occurrence of depression symptoms within families. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Personality traits underlying both anxiety disorders and depression are more malleable than previously presumed. This study examined associations between changes in personality traits (i.e. negative affectivity and detachment) and alleviation of anxiety and depression symptoms following cognitive behaviour therapy (CBT).
This paper highlights the need for more research, as there was little empirical evidence establishing the specific intervention mechanisms. With further investigation, this could support clinicians to refine existing interventions for depression and anxiety to ensure the most effective underlying mechanisms are incorporated into treatment plans.
The qualitative findings imply the importance of co-design and co-evaluation with young people using therapeutic services. It suggests that service-user forums are necessary to help clinicians identify treatment barriers, and therefore should be encouraged to ensure the best outcomes for service-user and service by designing the most effective interventions.
Psychological interventions for depression/anxiety should target more and more diverse intrapersonal emotion regulation skills. More specifically, therapies focusing on improving engagement emotion regulation skills and reducing disengagement emotion regulation skills and emotion dysregulation seem particularly impactful. Additionally, long treatments with six or more sessions, cognitive behavioural therapies and group interventions should be favoured.
The evidence for the effect of therapeutic alliance in group cognitive behaviour therapy (CBT) for anxiety disorders is unclear. Identifying whether the alliance–outcome relationship depends on (1) which components are assessed, (2) who is measuring the alliance and (3) when the alliance is measured will help to clarify the role of the client–therapist relationship in therapy. The present study explored the effects of alliance component (agreement vs. bond), rater perspective (client vs. therapist) and timing (early vs. late therapy) on the alliance–outcome relationship.. To read the full article, log in using your MPFT NHS OpenAthens details.
There are increased prescribing rates of antidepressants associated with an increase in the diagnosis of depression. However, antidepressants are not effective for many people. There is a gap in the existing literature for a synthesis of the experiences of those with lived experience of antidepressant use to better understand their use and impact given their ubiquitous use in mental health, primary care and other secondary and tertiary care settings. Mental health nurses play direct or indirect roles in both advocating for antidepressant use and monitoring adherence.
Most studies on the health impact of occupational stress use single-point measures of stress at work. This study analyses the associations of properties of entire employment trajectories over an extended time period with a composite score of allostatic load (AL). To read the full article, log in using your NHS OpenAthens details.
This descriptive study aimed to present the characteristics and needs of refugee women who attended a psychosocial walk-in clinic addressing pregnant refugees’ and new mothers’ maternity mental healthcare needs in a state registration and reception centre in Germany. To read the full article, choose “Institutional Login” and search for “Midlands Partnership”.
Seasonal affective disorder (SAD) is common and debilitating. The standard of care includes light therapy provided by a light box; however, this treatment is restrictive and only moderately effective. Advances in LED technology enable lighting solutions that emit vastly more light than traditional light boxes. Here, we assess the feasibility of BROAD (Bright, whole-ROom, All-Day) light therapy and get a first estimate for its potential effectiveness.
This meta-analysis showed that school-based depression and anxiety prevention programmes have small but positive effects. However, these effects dissipate in the long term, at 12 months follow-up. Additionally, targeted programmes seem to be more efficient compared to universal ones, and programmes delivered by external professionals show better outcomes compared to programmes delivered by school staff.
Recognising that physical activity-based interventions are potentially effective in reducing anxiety symptoms in children and young people, especially for those suffering from mental health conditions, has important implications for children and their families or carers, and may inform and guide clinicians in their practice, as well as policy-makers, mental health services and advisory bodies.
Working memory (WM) deficits are recognized as serious cognitive impairment in patients with major depressive disorder (MDD). This review aims to clarify the effects of impaired WM function in patients with MDD and explore non-invasive and effective treatments that can be adopted in clinical practice. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Generalized anxiety disorder (GAD) is associated with the lowest treatment response rate among all anxiety disorders. Understanding mechanisms of improvement may help to develop more effective and personalized treatments. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Magnetic seizure therapy for treatment-resistant depression: a Cochrane Review - Volume 29 Issue 2 To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Generalized anxiety disorder (GAD) is characterized by persistent worry and anxiety, often with a chronic course. We tested the role of two suggested underlying factors in GAD, interpersonal problems and negative metacognitive beliefs, as predictors of trait-worry and trait-anxiety. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Meta-analytic research shows early response to psychotherapy to predict depression and anxiety outcomes at posttreatment. However, little is known about which variables explain differences in early response. Moreover, for patients with generalized anxiety disorder (GAD), there is limited research on whether early response predict longer-term changes in symptoms. In this study, we used anxiety and controllability beliefs assessed in daily life at intake to predict early response to treatment (until session 5), and we further examined if early response predicts longer-term changes in symptoms (until posttreatment, when adjusting for intake symptom severity) in patients with GAD. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This review highlights the potential for community interventions to reach marginalised groups that may not access health services. Despite the lack of robust evidence, the included trials did show promising effects of community interventions on anxiety and depression
Depression is a leading cause of disability worldwide that negatively impacts quality of life. Talk therapy such as cognitive behavioural therapy is an effective treatment for depression. The Internet is an important tool for mental healthcare delivery. Internet-delivered or online talk therapy interventions are associated with lower costs and improved accessibility.
Current reviews do not address the effectiveness of Internet-delivered cognitive behavioural therapy (iCBT) on quality of life (QoL). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Major depressive disorder is the most prevalent of all mental illnesses.
10%–20% of patients with depression and 1% of the population overall have treatment-resistant depression (TRD).
DBS is an emerging investigational treatment for TRD with documented clinical efficacy and safety.
The framework of the recovery model includes both clinical and personal recovery. Personal recovery is a self-process in which hope, empowerment and optimism are embraced to overcome the impact of mental illness on one's sense of self.
Although clinical and functional outcomes of DBS for TRD have been well documented in the previous studies, personal recovery as an outcome has been explored only in a handful of studies.
Mental disorders are a major cause of work disability among the working-age population. We used population-based register data to examine the association between statutory rehabilitative psychotherapy and change in depression or anxiety-related work disability. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The identified relationship between parental mood disorders and offspring anxiety disorders provides valuable insights that mental health practitioners can integrate into their practice. Understanding these risk factors and underlying mechanisms aids mental health professionals in tailoring treatments and interventions according to the family background and specific needs of their clients.
This qualitative systematic review shows that antidepressants might not always help depression. For this patient population, it may be important for health professionals to work with patients to explore other treatments for managing their depression. Treatment could include cognitive behavioural therapy, which was shown in a systematic review to be an effective intervention for TRD at short-term, mid-term, and long-term follow-up (Li et al., 2018).
Prevention of new depressive disorders is very much needed because current treatments can only reduce the disease burden of depression to a limited extent.
Research has shown that preventive interventions are effective, especially in indicated prevention, but also selective prevention. However, the impact of these interventions is limited because the uptake is low.
A new generation of randomized community trials are needed to examine suites of innovative preventive interventions.
Megan Skelton explores a study that characterises developmental trajectories & the role of neuropsychiatric genetic risk variants in early-onset depression.
Open access. Although currently available evidence suggests that physical exercise can be beneficial for depressed patients and might be comparable to antidepressant treatment, the best way of implementing this recommendation in clinical practice is not known. This study therefore aims to ascertain the non-inferiority of supervised physical exercise to antidepressant drug treatment, in terms of reducing depressive symptoms among patients presenting with clinical criteria of a depressive episode (ICD-10), across a follow-up period of 6 months.
Open access. Childhood maltreatment is one of the strongest predictors of adulthood depression and alterations to circulating levels of inflammatory markers is one putative mechanism mediating risk or resilience.
We evaluated birth cohort differences in depressive symptom burden, prevalence of depression diagnoses, and neuroticism, among Swedish 70‐year‐olds examined between 1976 and 2016. . To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Open access. Anxiety and depressive disorders are common mental disorders. A substantial part of patients does not achieve symptomatic remission after treatment in specialized services. Current care as usual (CAU) for these patients consists of long-term supportive contacts. Termination of CAU is often not considered to be an option due to persistent symptoms, a low level of functioning, and the absence of further treatment options. A new intervention, ZemCAD, offers a program focused on rehabilitation and self-management, followed by referral back to primary care.
Neuroticism is a heritable personality trait, characterized by negative emotions such as worrying, feelings of guilt, loneliness and being easily hurt. Increased levels of neuroticism are associated with poor mental health – development of depression in particular – but it remains uncertain whether this association represents a causal effect [1]. Here, we use Mendelian randomization (MR) to investigate whether neuroticism is a causal risk factor for development of depression.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Studies involving clinically recruited samples show that genetic liability to schizophrenia overlaps with that for several psychiatric disorders including bipolar disorder, major depression and, in a population study, anxiety disorder and negative symptoms in adolescence.. To read the full article, log in using your MPFT NHS OpenAthens details.
Psychological Medicine; Cambridge Vol. 49, Iss. 3, (Feb 2019): 449. DOI:10.1017/S0033291718001058
The aim of this study was to explore the relationship between patient self-reported Patient Health Questionnaire-9 (PHQ-9) symptoms and doctor diagnosis of depression using a tree analysis approach.. To read the full article, log in using your NHS OpenAthens details.
Psychological Medicine; Cambridge Vol. 49, Iss. 3, (Feb 2019): 491. DOI:10.1017/S0033291718001113
Insomnia and depression are highly comorbid and mutually exacerbate clinical trajectories and outcomes. Cognitive behavioral therapy for insomnia (CBT-I) effectively reduces both insomnia and depression severity, and can be delivered digitally. This could substantially increase the accessibility to CBT-I, which could reduce the health disparities related to insomnia; however, the efficacy of digital CBT-I (dCBT-I) across a range of demographic groups has not yet been adequately examined. This randomized placebo-controlled trial examined the efficacy of dCBT-I in reducing both insomnia and depression across a wide range of demographic groups.. To read the full article, log in using your NHS OpenAthens details.
Major depression (MD) is often accompanied by deficits in cognitive functioning. Cognitive behavioral therapy (CBT) has beneficial effects on MD. The aim of this study was to examine whether cognitive behavioral therapy affects verbal learning and memory in patients with MD and whether CBT that emphasizes exercise during behavioral activation has additional effects on verbal performance.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Findings This systematic review and meta-analysis of 27 randomized placebo-controlled clinical trials involving a total of 1890 men found that testosterone treatment was associated with a significant reduction of depressive symptoms, particularly in participants who received higher-dosage regimens.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Open access. Humor trainings have positive effects on mental health and well-being. However, studies investigating the effects of humor trainings in clinical samples are still rare. This study investigated the efficacy and feasibility of a humor training for people suffering from depression, anxiety and adjustment disorders.
Letter. . To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Mood disorders are strongly associated with suicide, the prevention of which is predicated on timely detection of suicidal activity (ideation, behavior). Building on our previous work, we sought to determine the nature of neural responses to an emotional‐cognitive task in patients with varying degrees of suicidal activity.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Psychology of Consciousness: Theory, Research, and Practice (Feb 25, 2019). DOI:10.1037/cns0000185
It is widely assumed that belief in God allows people to better cope with life’s stresses. This stress-buffering effect is not limited to religion; when faced with stress, nonreligious people cling on to other belief systems, notably belief in science. We report an experimental test of whether people are able to down-regulate an acute stress experience by reflecting on their beliefs. We used the Trier Social Stress Test to induce stress in religious and scientist participants from the United Kingdom by having them discuss arguments for and against the United Kingdom leaving the European Union (“Brexit”). To read the full article, log in using your NHS OpenAthens details.
To synthesize recent knowledge on the association of urbanization (and neighbourhood factors) and anxiety and stress-related disorders. . Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
To examine the association between hearing aids (HAs) and time to diagnosis of Alzheimer disease (AD) or dementia, anxiety or depression, and injurious falls among adults, aged 66 years and older, within 3 years of hearing loss (HL) diagnosis.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Open access. Major depressive disorder (MDD) has been related to structural brain characteristics that are correlated with the severity of disease. However, the correlation of these structural changes is less well clarified in treatment-resistant depression (TRD).
The aim of this randomized controlled trial was to examine the impact of daily supportive text messages over a 6-month treatment period on mood and alcohol consumption in individuals with a dual diagnosis of alcohol use disorder (AUD) and depression following completion of an inpatient treatment programme.. Please contact the library to request a copy of this article - http://bit.ly/2HjNDf3
Open access. Meta-analyses of randomised controlled trials suggest that psychological interventions to reduce children’s risk of depression are effective. Nevertheless, these effects are modest and diminish over time. The Medical Research Council recommends a mixed-methods approach to the evaluation of complex interventions. By gaining a more thorough understanding of participants’ perspectives, qualitative evaluations of preventive interventions could improve their efficacy, longevity and transfer into clinical practice.
One of the most exciting recent breakthroughs from research funded by the National Institute of Mental Health, or NIMH, is the development of a fast-acting medication for treatment-resistant depression based on ketamine
Circadian rhythms are altered in Major Depressive Disorder (MDD) as showed by changes in circadian patterns of gene expression in the human brain of subjects affected by MDD (1). Circadian rhythms are produced centrally by clock genes and some single nucleotide polymorphisms located in clock genes have been associated with vulnerability to MDD (2). Similarly, one study suggests that clock gene expression in tissues related to pregnancy is altered in mice during pregnancy, although this has not been tested yet in humans (3). No data have been published thus far regarding the expression of clock genes during perinatal depression, while history of depression has been found to be associated with the increased expression of gene CLOCK that would be responsible for an anticipation of the sleep waking rhythms and of late insomnia typical in MDD.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Open access. Time-limited psychotherapy for depression is effective. However, comorbid personality disorders affect therapy outcomes negatively. Studies of follow-up effects and results relating to the influence of comorbid personality disorder and treatment modality are scarce.
Open access. Several studies have suggested that depression is associated with an increased risk for fracture; however, the results are conflicting. This study aimed to conduct a meta-analysis of cohort studies assessing the association between depression and the risk for fracture.
Pioneering research over the past two decades has shown that memories are far more malleable than we once thought, thereby highlighting the potential for new clinical avenues for treatment of psychopathology. We first briefly review the historical foundation of memory reconsolidation—a concept that refers to hypothetical processes that occur when a memory is retrieved and restored. Then, we provide an overview of the basic research on memory reconsolidation that has been done with humans and other animals, focusing on models of fear, anxiety-related disorders, and addiction, from the perspective that they all involve disorders of memory. This basic research has fuelled early stage developments of novel treatment techniques.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Electroconvulsive therapy (ECT) is an effective treatment for severe depressive disorders, with older age being predictive of a better outcome. Two earlier small studies have suggested an increased prevalence of dementia in patients having received ECT, but were flawed by major methodological shortcomings. Recent data on both short-term and long-term impact of ECT on cognitive function in older patients are reassuring,1 even in the presence of age-related brain changes.2. To read the full article, log in using your NHS OpenAthens details.
Ketamine has been documented for its rapid antidepressant effects. However, optimal dose and delivery route have not yet been thoroughly investigated. The objectives of this study were to document the safety and test the antidepressant and antisuicidal effects of a single rapid 1-minute injection of ketamine 0.5 mg/kg in treatment-resistant depression (TRD). . MPFT staff can use the OVID link, or you can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
It has taken more than 40 years for Lisa Rodrigues to talk about her mental health difficulties. She hopes her candour will help others who are struggling at the top. A year before she left her position as the chief executive of a mental health trust, Lisa Rodrigues wrote about her depression and anxiety, which began when she was 15 years old. ‘I’d been secretive about it,’ says Ms Rodrigues, who qualified as a nurse in 1977 at Great Ormond Street Hospital in London. ‘But I thought I’d kept it secret for long enough. It’s about destigmatising.’ To read the full article, log in using your MPFT NHS OpenAthens details.
Canadian Psychology/Psychologie canadienne Vol. 59, Iss. 4, (Nov 2018): 301-314. DOI:10.1037/cap0000155
Face-to-face cognitive-behavioral therapy (CBT) and interpersonal therapy (IPT) are time-limited, structured psychotherapies recommended for the management of adult major depressive disorder (MDD) and generalized anxiety disorder (GAD). We conducted a systematic review to evaluate the reporting and methodological quality, and cost-effectiveness of economic evaluations that examined these two thoroughly researched psychotherapies.. To read the full article, log in using your MPFT NHS OpenAthens details.
The purpose of this study was to explore whether adolescent‐perceived family functioning moderates the depression treatment effects on suicidal ideations.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
This is a valuable insight into the views of different healthcare professionals involved in managing depression.
It may help to offer some explanation about why psychological referrals are so low among older people despite the high prevalence of depression symptoms.
Free access. To examine the psychometric properties of the Emotion Regulation Questionnaire (ERQ) among a sample of older community‐dwelling males and females and to also assess gender differences in the association between emotion regulation and positive and negative affect.
These are self-reported symptoms of depression. The participants have not been clinically diagnosed as depressed.
This means it's not clear from the study if these slightly higher levels of depression symptoms had any impact on the women's daily life and wellbeing.
As working patterns and depression symptoms were measured at the same time, we do not know if the long hours were the cause of the symptoms. Many other personal, health and lifestyle factors may be involved.
Commentary on: Bockting CLH, Klein NS, Elgersma HJ, et al. Effectiveness of preventive cognitive therapy while tapering antidepressants versus maintenance antidepressant treatment versus their combination in prevention of depressive relapse or recurrence (DRD study): a three-group, multicentre, randomised controlled trial. Lancet Psychiatry. 2018; 5:401-410.. To read the full article, log in using your NHS OpenAthens details.
Generalised anxiety disorder is a disease that can be associated with substantial dysfunction. Pharmacological treatment is often the first choice for clinicians because of the cost and resource constraints of psychological alternatives, but there is a paucity of comparative information for the multiple available drug choices.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
There is growing interest in the association between gait disturbance and depression in later life. The aim of this study is to clarify the longitudinal relationship between specific gait parameters and incident depression within a population‐representative sample of older people.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Depression usually has its onset during adolescence or early adulthood. Recurrences are common and contribute to its substantial disability. Mild symptoms may be the beginning of a new episode or lingering consequences of a partially remitted episode. Waiting for symptoms to become full blown or leaving mild symptoms untreated may miss opportunities to improve patient outcome. An understanding of the natural course of untreated depression, together with an appreciation of differences between clinical research and practice, facilitates translation of research findings into effective clinical care.. Login at top right hand side of page using your MPFT NHS OpenAthens for full text.
Open access. About one in five patients with depression experiences a chronic course. Despite the great burden associated with this disease, there is no current screening instrument for Persistent Depressive Disorder (PDD). In the present study, we examine a short screening test, the persistent depression screener (PDS), that we developed for DSM-5 PDD. The PDS is comprised of one question that is administered following an initial self-assessment for depression.
Psychodermatology is the interaction between skin and mind. Psychodermatological conditions are present in many patients with a mental health condition or mental health concerns. However, conditions such as dermatitis artefacta and trichotillomania are commonly misunderstood, and access to treatment may be limited. Nurses play a vital role in supporting patients and families by assessing, treating and managing such conditions, while also providing education on the condition and the treatment that is required. This article describes common psychodermatological conditions and the variety of care that can be carried out. To read the full article, log in using your MPFT NHS OpenAthens details.
Older age and Major depressive disorder (MDD) are both risk factors for the development of cardiovascular diseases. Testosterone has been associated with MDD and Metabolic Syndrome (MetS) in men, though associations in women are less clear. Therefore, we investigated whether testosterone is associated with MetS and whether this association is different for depressed and non‐depressed older men and women.. To read the full article, log in using your MPFT NHS OpenAthens details.
The present review complements previous reviews on prediction research in anxiety disorders with a focus on clinical, imaging and genetic as well as epigenetic factors and aims to provide recommendations for the design of future integrative studies in adults as well as children.. MPFT staff can use the OVID link, or you can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Transcript and recording of webinar. In this short webinar, I’ll be talking a little bit about psychological, or “talk therapy” treatment for clinical depression in adolescents—specifically, I’ll be sharing information about a type of talk therapy called Behavioral Activation, that we offer in our outpatient clinic to teenagers enrolled in our studies.
Transcript and recording. "I’ll be talking a little bit about major depression—what it is, how frequently we see it in young people, signs and symptoms, and next steps if you think someone you care about may be experiencing depression."
Commentary on: Bockting CLH, Klein NS, Elgersma HJ, et al. Effectiveness of preventive cognitive therapy while tapering antidepressants versus maintenance antidepressant treatment versus their combination in prevention of depressive relapse or recurrence (DRD study): a three-group, multicentre, randomised controlled trial. Lancet Psychiatry. 2018; 5:401-410.. To read the full article, log in using your NHS OpenAthens details.
Interpretation training to target repetitive negative thinking in generalized anxiety disorder and depression
Hirsch, Colette R; Krahé, Charlotte; Whyte, Jessica; Loizou, Sofia; Bridge, Livia; et al. Journal of Consulting and Clinical Psychology Vol. 86, Iss. 12, (Dec 2018): 1017-1030. DOI:10.1037/ccp0000310
Full text
Objective: Repetitive negative thinking (RNT) for example, worry in generalized anxiety disorder (GAD) and rumination in depression, is often targeted during psychological treatments. To test the hypothesis that negative interpretation bias contributes to worry and rumination, we assessed the effects of inducing more positive interpretations in reducing RNT.. To read the full article, log in using your NHS OpenAthens details.
To compare the odds of depression in obese and overweight children with that in normal-weight children in the community.. To read the full article, log in using your NHS OpenAthens details.
Commentary on Cochrane corner. The pharmacological treatment of depression is often hampered by side-effects and unsatisfactory response to treatment. Vortioxetine is one of the newest antidepressants on the market, purportedly with a different mechanism of action compared with other antidepressants. This month's Cochrane Corner review examines the evidence available for the use of vortioxetine as a first-line treatment for depression in adults. This commentary puts the Cochrane review's findings into their clinical context and revises them in view of earlier and later studies.. To read the full article, log in using your MPFT NHS OpenAthens details.
Depression is considered to have the highest disability burden of all conditions. Although treatment-resistant depression (TRD) is a key contributor to that burden, there is little understanding of the best treatment approaches for it and specifically the effectiveness of available augmentation approaches.. To read the full article, log in using your MPFT NHS OpenAthens details.
Most people with bipolar disorder spend a significant percentage of their lifetime experiencing either subsyndromal depressive symptoms or major depressive episodes, which contribute greatly to the high levels of disability and mortality associated with the disorder. Despite the importance of bipolar depression, there are only a small number of recognised treatment options available. Consecutive treatment failures can quickly exhaust these options leading to treatment-resistant bipolar depression (TRBD). Remarkably few studies have evaluated TRBD and those available lack a comprehensive definition of multi-therapy-resistant bipolar depression (MTRBD).. To read the full article, log in using your MPFT NHS OpenAthens details.
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Open access. Psychological Medicine; Cambridge Vol. 49, Iss. 1, (Jan 2019): 149-161. DOI:10.1017/S0033291718000612
Which neighbourhood factors most consistently impact on depression and anxiety remains unclear. This study examines whether objectively obtained socioeconomic, physical and social aspects of the neighbourhood in which persons live are associated with the presence and severity of depressive and anxiety disorders.
Psychological Services (Nov 8, 2018). DOI:10.1037/ser0000261
Depression is common in primary care settings, but barriers prevent many primary care patients from initiating treatment. Smartphone apps stand as a possible means to overcome such barriers. However, there is limited evidence to understand the use and efficacy of these apps. The purpose of the current study was to pilot an evaluation of the usage and efficacy of apps for depression based upon behavioral or cognitive intervention skills, compared to a wait-list control.. To read the full article, log in using your MPFT NHS OpenAthens details.
To estimate the 6‐month prevalence of Generalized Anxiety Disorder (GAD) in primary care patients aged 70 years and over in Quebec, and to describe their clinical profile, including types of worries.. To read the full article, log in using your MPFT NHS OpenAthens details.
Newer-generation antidepressants used in monotherapy or in combination with other newer-generation antidepressants or other psychotropic drugs are usually preferred as first- or second-step treatment options in resistant depression. According to our clinical experience, tricyclic antidepressants still are one of our preferred first choices in treatment-resistant moderate to severe unipolar major depressive episodes.. MPFT staff can use the OVID link, or you can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
People should look out for signs of depression and dementia among older family members and friends over Christmas, NHS England expert Professor Alistair Burns urged today.
Problems that may have been hidden can come to the surface or be easier to spot as families or friends get together over the festive season, Prof Burns said.
Depression should not be written off as inevitable in old age and can be treated effectively. Emotional changes can also be the first indication that someone has dementia.
Open access. Bipolar and other psychiatric disorders are associated with considerably increased risk of suicidal behaviour, which may include self-poisoning with medication used to treat the disorder. Therefore, choice of medication for treatment should include consideration of toxicity, especially for patients at risk. The aim of this study was to estimate the relative toxicity of specific drugs within two drug categories, antipsychotics and mood stabilizers, using large-scale databases to provide evidence that could assist clinicians in making decisions about prescribing, especially for patients at risk of suicidal behaviour.
Psychiatric Rehabilitation Journal (Dec 20, 2018). DOI:10.1037/prj0000331
Objective: Self-management support is recognized as an important component of the management of mood and anxiety disorders. The goal of this feasibility study was to evaluate the acceptability, implementation and perceived usefulness of a new comprehensive self-management tool ( Getting better my way) in four care settings in Quebec, Canada. To read the full article, log in using your NHS OpenAthens details.
Psychological Medicine; Cambridge Vol. 48, Iss. 16, (Dec 2018): 2684-2692. DOI:10.1017/S0033291718000296
Background
Reports of changes in patients’ social behavior during deep brain stimulation (DBS) raised the question whether DBS induces changes in personality. This study explored if (1) DBS is associated with changes in personality in patients suffering from treatment-resistant depression (TRD), (2) how personality dimensions and depression are associated, and (3) if TRD patients’ self-ratings of personality are valid.. To read the full article, log in using your NHS OpenAthens details.