The International Anxiety Questionnaire (IAQ) and International Depression Questionnaire (IDQ) are self-report measures of ICD-11 Generalized Anxiety Disorder (ICD-11 GAD) and ICD-11 Single Episode Depressive Disorder (ICD-11 DD). This study tested the psychometric properties of these scales in two samples of bereaved adults from the United Kingdom and the Republic of Ireland.
Although this study suggested that long-term psychoanalytic psychotherapy in combination with treatment as usual was not cost-effective compared with TAU, there may be more explanations to this. Given the sustained long-term effects over the follow-up period and the trajectory of treatment benefits in the LTPP+TAU group, it seems plausible that the timescale of this study was too short to accurately portray the long-term benefits of LTPP.
Predicting the course and complications of perinatal depression through the identification of clinical subtypes has been previously undertaken using the Edinburgh Postnatal Depression Scale and has the potential to improve the precision of care and improve outcomes for women and their children. https://onlinelibrary.wiley.com/doi/10.1002/cpp.2893?af=R
Bouldering psychotherapy (BPT) for depression has proven effective, but nothing is known about its potential predictors of response. This study should identify predictors of response to BPT, cognitive behavioural therapy (CBT) and an active control (home-based exercise programme; EP) using a literature-based model.
Individuals with major depressive disorder (MDD) and childhood maltreatment have been proposed to constitute a subgroup with worse illness course and outcomes. To elucidate a potential social cognitive vulnerability in this subgroup, this study compared the emotion decoding abilities of MDD patients with and without a history of childhood maltreatment.
If we have a better understanding of how anxiety and depression may develop over the course of childhood and adolescence, and who may be at greatest risk of adverse outcomes in adulthood, this may inform targeted early identification and prevention strategies. The authors suggest that this could beneficially impact policy and practice at certain touchpoints, such as the transition from children’s to adult’s mental health services, which has been highlighted by previous studies as an “international concern” due to the consequences of lack of continuity of care (Hendrickx et al., 2020 p. 163).
Some anxiety disorders may improve or remit without intervention, meaning a brief period of ‘watchful waiting’ may be prudent in certain situations
Specific phobia and panic disorder with agoraphobia do not show signs of improving without intervention, meaning that treatment should be provided as soon as possible for individuals with these conditions.
It’s worth commenting on the finding that only 15% of control participants experienced ‘clinically meaningful’ improvements in their anxiety, meaning 85% will still experience symptoms of anxiety. For those whose anxiety does not improve significantly or remit, this waiting period will not be a neutral limbo – it may be a highly difficult and distressing time for them, and this must be taken into account when considering the implementation of such findings.
Difficulties regulating emotions during periods of distress may contribute to the high rates of co-occurring depression and anxiety in autistic adults. The emotional support plan (ESP) is a brief intervention designed to support autistic adults to use positive coping skills during periods of distress. Thirty-six autistic adults participated in studies to assess the acceptability of the ESP intervention... To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Depression and anxiety are common, with one in six people experiencing symptoms in any given week. Of these people, 8.32 million are prescribed antidepressants. People living with HIV are likely to experience psychiatric disorder, with one in three experiencing depression and anxiety, and being at greater risk of developing post-traumatic stress disorder... This article seeks to raise awareness of sexual side-effects of psychotropic medications and draw attention to ethical issues related to post selective serotonin reuptake inhibitor sexual dysfunction (PSSD)
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Hospitalization is a stressful event that may lead to deterioration in older adults’ mental health. Drawing on the stress-buffering hypothesis, we examined whether family support during hospitalization would moderate the relations between level of independence and in-hospital depressive symptoms.
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Efficacy and safety of a 4-week course of repeated subcutaneous ketamine injections for treatment-resistant depression (KADS study): randomised double-blind active-controlled trial. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Gaining awareness of psychosis (i.e., insight) is linked to depression, particularly in the post-acute phase of psychosis. Informed by social rank theory, we examined whether the insight–depression relationship is explained by reduced social rank related to psychosis and whether self-compassion (including uncompassionate self-responding [UCS] and compassionate self-responding [CSR]) and mindfulness buffered the relationship between social rank and depression in individuals with first episode psychosis during the post-acute phase.
Postpartum depression (PPD) is a common perinatal complication with adverse maternal and infant outcomes. This study investigated the efficacy and safety of zuranolone, a positive allosteric modulator of synaptic and extrasynaptic GABAA receptors and neuroactive steroid, as an oral, once-daily, 14-day treatment course for patients with severe PPD. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The review showed that robust evidence for the effectiveness of iCBT as an add-on to TAU is still limited, with results not necessarily generalisable to people from different backgrounds based on age, gender, education, and mental healthcare settings. Clearly more research is needed, as remotely delivered, self-guided iCBT has the promise to increase accessibility and be more cost-effective.
The findings suggest the involvement of both innate and adaptive immune cells in the development of depression.
Identifying dysfunctional immune cell subsets could help select patients with depression who show signs of immune dysfunction for future immunotherapy trials. However, further studies are needed to understand causality and how immune cell dysfunction relates to cytokine and neurotransmitter dysregulation.
To manage ‘treatment-resistant depression’, research has demonstrated that a multidisciplinary approach should be utilised (i.e., administration of medication as well as psychological support). In the current study, psilocybin was administered during a single session of psychological support. More research needs to be conducted to investigate the effectiveness of using psilocybin alongside a course of psychological support (e.g., Cognitive Behavioural Therapy).
No previous studies have reported predictors and moderators of outcome of psychological therapies for depression experienced by adults with intellectual disabilities (IDs). We investigated baseline variables as outcome predictors and moderators based on a randomised controlled trial where behavioural activation was compared with guided self-help. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study used structural equation modelling to test the prediction that intolerance of uncertainty and emotion regulation constitute more direct causes of anxiety in autism that mediate the influences of sensory processing difference and alexithymia as more sequential contributing factors. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Childhood emotional maltreatment (CEM) is a risk factor for the pathogenesis of depressive disorders. However, it is not clear whether CEM is more strongly related to specific symptoms of depression and whether specific traits or cognitive states may mediate the association between CEM and depressive symptoms. In our cross-sectional study, including 72 patients with a current depressive episode, we investigated if CEM is specifically related to cognitive symptoms of depression.
Overall, this research brings to light many ways in which access can be improved. However, as the authors mention, it is important to keep in mind that the process of improving access is not a “one size fits all” approach. Instead, programs that aim to improve access should carefully consider their target audience and combine a variety of complementary strategies. In conclusion, the authors talk about practice guidelines. They suggest that each category of healthcare providers would benefit from specific guidelines on improving access to CBT through their specific roles.
By investigating parents’ depression and how it can be associated with children’s emotional difficulties, this study showed that if untreated, mental ill-health can have significant long-lasting effects on the mother, father and children.
As this study points out, the activating and associating depressive symptoms between family members can be targeted for more rapid recovery, and may be key to identifying who might be more at risk of developing depression in young children, and later unintentionally influencing the transmission of depression.
Despite limitations, the findings from this study have important clinical and research implications for treating adolescent depression.
For clinicians, it may be beneficial at the beginning of a case of treatment for adolescent depression to develop a set of personalised outcome goals with the patient, with recognition that this is likely to vary greatly between individuals. Treatment could then be jointly chosen by the patient and clinician to ensure these priorities are addressed. This approach could also take into account what the patient thinks their key problem areas are, and what they consider to be valuable improvements. This would also provide a good framework when reviewing clinical decisions of whether to continue or change treatments.
The provision of cCBT through the NHS could help some young people who need support for anxiety and depression to access the treatment they need more easily. This could be of particular benefit to young people who would not otherwise be able to access traditional face-to-face therapies or who would prefer something remote. However, this review makes it clear that the evidence base for cCBT is currently weak and that high-quality future research is needed, so caution needs to be taken by practitioners before recommending cCBT programs.
Previously improving UK mortality trends stalled around 2012, with evidence implicating economic policy as the cause. This paper examines whether trends in psychological distress across three population surveys show similar trends. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This study aimed to investigate whether separation anxiety (SA) constitutes a dimension related to age at onset of panic disorder (PD), in homogeneous subgroups of outpatients with PD, based on their age of onset and symptom severity.
The 2019 coronavirus (COVID-19) pandemic led to elevated levels of psychological distress on a global scale. Given that individuals with pre-existing physical conditions are at risk for worse COVID-19 outcomes, those dealing with the stress of physical health problems (including knowing someone with health problems) may experience more severe distress during the pandemic. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Personality traits underlying both anxiety disorders and depression are more malleable than previously presumed. This study examined associations between changes in personality traits (i.e. negative affectivity and detachment) and alleviation of anxiety and depression symptoms following cognitive behaviour therapy (CBT).
Intuitively, it makes sense for researchers to be investigating how effective digital mental health support is for a technology-savvy generation. Long waiting lists show that the need for more accessible interventions is there, but these findings indicate that current internet-delivered interventions may not be effective enough to meet this need.
The clinical effect of electroconvulsive therapy (ECT) has been confirmed for a majority of patients with several psychiatric disorders. ECT is mostly used in patients with severe depression.
Choosing, persevering with and completing ECT depends on the patients' motivation for undergoing this therapy. However, the factors influencing patients' motivation for ECT have not yet been studied. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Major depressive disorder is the most prevalent of all mental illnesses.
10%–20% of patients with depression and 1% of the population overall have treatment-resistant depression (TRD).
DBS is an emerging investigational treatment for TRD with documented clinical efficacy and safety.
The framework of the recovery model includes both clinical and personal recovery. Personal recovery is a self-process in which hope, empowerment and optimism are embraced to overcome the impact of mental illness on one's sense of self.
Although clinical and functional outcomes of DBS for TRD have been well documented in the previous studies, personal recovery as an outcome has been explored only in a handful of studies.
Depression is a leading cause of disability worldwide that negatively impacts quality of life. Talk therapy such as cognitive behavioural therapy is an effective treatment for depression. The Internet is an important tool for mental healthcare delivery. Internet-delivered or online talk therapy interventions are associated with lower costs and improved accessibility.
Current reviews do not address the effectiveness of Internet-delivered cognitive behavioural therapy (iCBT) on quality of life (QoL). To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
To investigate the impact of persistent anxiety, depression, and comorbid anxiety and depression across childhood and adolescence on the development of multiple adverse outcomes in young adulthood. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Mother and father depression symptoms often co-occur, and together can have a substantial impact on child emotional well-being. Little is understood about symptom-level mechanisms underlying the co-occurrence of depression symptoms within families. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
This review highlights the potential for community interventions to reach marginalised groups that may not access health services. Despite the lack of robust evidence, the included trials did show promising effects of community interventions on anxiety and depression
It is really encouraging that CBT performs better than control conditions for reducing depression symptoms up to 12 months later and across many different formats and populations. CBT has been well tested for depression, and whilst there is still much room for improvement (e.g., the effect sizes are much more modest for child and adolescent trials than for trials in adults), we can be reasonably confident, given these findings, that CBT is worth investing in as a treatment approach. That said, one size doesn’t fit all, and again, it is encouraging that self-help CBT, even without human support input, was at least moderately good at reducing depression symptoms.
These findings suggest that interventions designed to prevent or reduce depressive symptoms in people with autism spectrum disorder and mild intellectual disability should include among their goals emotional regulation. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
In the general population, low self-esteem has been linked with poorer mental and physical health. This systematic literature review aimed to summarise and evaluate the findings of studies that examined self-esteem in adults with intellectual disabilities and links with mental health outcomes. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The associations among psychotic experiences (i.e., hallucinations and delusions), trauma exposure, and posttraumatic stress symptoms are complex and multidirectional. Using network analysis to understand how psychotic experiences and symptoms of posttraumatic stress disorder (PTSD) relate to one another may identify new interventional targets to treat comorbidity and its underlying pathological processes. This study aimed to use network analysis to examine the associations among psychotic experiences; negative symptoms of psychosis; and symptoms of PTSD, anxiety, and depression.
Generalized anxiety disorder (GAD) is characterized by persistent worry and anxiety, often with a chronic course. We tested the role of two suggested underlying factors in GAD, interpersonal problems and negative metacognitive beliefs, as predictors of trait-worry and trait-anxiety. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
T. Itatsu, A. Nagahara, M. Hojo, A. Miyazaki, T. Murai, M. Nakajima, and S. Watanabe. Internal medicine (Tokyo, Japan), 50 (7):
713-7(January 2011)JID: 9204241; 0 (Serotonin Uptake Inhibitors); 2011/04/01 epublish; ppublish; Confusió absoluta entre cas-control i exposats-no exposats<br/><br/><br/>Tipus d'estudis.