People with social anxiety disorder (SAD) fear social interactions and may be reluctant to seek treatments involving exposure to social situations. Social exposure conducted in virtual reality (VR), embedded in individual cognitive–behavioural therapy (CBT), could be an answer. You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Evidence from preclinical and clinical studies supports a role for vitamin D deficiency in many mental disorders. In this review, we discuss the role of vitamin D in the aetiology and treatment of schizophrenia and depression and their physical health comorbidities. Although observational studies support a potential association between vitamin D and schizophrenia and depression, sufficient high-quality evidence from clinical trials does not yet exist to establish a place for vitamin D supplementation in optimising clinical response or promoting physical health. Completed randomised controlled trials are needed to provide insights into the efficacy and safety of vitamin D in the management of mental disorders.. To read the full article, log in using your MPFT NHS OpenAthens details.
The evidence for a prospective association of vitamin D deficiency with the occurrence of late-life depression is limited. We aimed to study the long-term association between vitamin D serum levels and depression in a large population-based study of older adults. Login using your SSSFT NHS OpenAthens for full text. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
This study is a useful summary of which nutrients have been tested as an add-on to antidepressants, and an overall indication of what the studies found. It shows that, for most of these nutrients, the evidence comes from small studies of varying quality and length, and that we need bigger, better studies to get a true picture of their effects.
For the nutrients where there was sufficient evidence to carry out a meta-analysis, the difficulty is that the way the results are presented makes it hard to tell how much of an effect the nutrients actually had on people's depression.
Commentary on Cochrane corner. The pharmacological treatment of depression is often hampered by side-effects and unsatisfactory response to treatment. Vortioxetine is one of the newest antidepressants on the market, purportedly with a different mechanism of action compared with other antidepressants. This month's Cochrane Corner review examines the evidence available for the use of vortioxetine as a first-line treatment for depression in adults. This commentary puts the Cochrane review's findings into their clinical context and revises them in view of earlier and later studies.. To read the full article, log in using your MPFT NHS OpenAthens details.
Antidepressants remain a mainstay of treatment to alleviate the heavy economic, societal and human tolls imposed by depression. Nevertheless, the high rates of treatment failure and poor adherence underscore the need for novel treatments. Vortioxetine is a new antidepressant that has a different pharmacological profile to conventional antidepressants and a long half-life that reduces the risk of discontinuation symptoms.
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Major depressive disorder (MDD) is widely prevalent and severely disabling, mainly due to its recurrent nature. A better understanding of the mechanisms underlying MDD-recurrence may help to identify high-risk patients and to improve the preventive treatment they need. MDD-recurrence has been considered from various levels of perspective including symptomatology, affective neuropsychology, brain circuitry and endocrinology/metabolism. However, MDD-recurrence understanding is limited, because these perspectives have been studied mainly in isolation, cross-sectionally in depressed patients. Therefore, we aim at improving MDD-recurrence understanding by studying these four selected perspectives in combination and prospectively during remission. Open Access Article
Stress generation in depression (i.e. the tendency for depression-prone individuals to experience more life stress that is in part influenced by the individual) has been well established. However, more research is necessary to clarify the role of specific types of life stress in this effect. The current study extends the stress generation hypothesis by examining whether the type of stress involved is contingent upon the nature of the individual’s particular vulnerability. Childhood emotional abuse and interpersonal vulnerability factors were predicted to be associated with prospective interpersonal dependent but not non-interpersonal or independent stress. These interpersonal factors were examined as mediators of the association between childhood emotional abuse and interpersonal stress generation. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
To examine the efficacy of using wake and light therapy as a supplement to standard treatment of hospitalized patients with depression. Login using your SSSFT NHS OpenAthens for full text. SSOTP - You can request a copy of this article by replying to this email. Please ensure you are clear which article you are requesting.
Ein Buch für alle, die immer wieder an ihre Belastungsgrenze stoßen und sich davor schützen möchten, langfristig in die Stressfalle und vielleicht sogar in einen Burnout zu geraten.
Imagery rescripting is a psychotherapeutic technique that aims to ameliorate negative emotions by altering (i.e., rescripting) inner representations of negative memories and images. Although the treatment was initially developed for traumatized individuals, face-to-face interventions have yielded promising results for patients with other diagnoses as well. The present study explored the feasibility and efficacy of the approach when used as a self-help intervention for depression.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai
Created through collaboration among the Depression and Bipolar Support Alliance (DBSA), University of Michigan Depression Center, and the U.S. National Institute of Mental Health (NIMH).
Dave Steele explores a literature review that focuses on how wearable technology can be used to measure and support social functioning in older adults.
Given the high prevalence and considerable disease burden associated with depression, attention has been shifting more and more to its prevention, with recent meta-analyses suggesting that a potentially fruitful avenue to explore might involve targeting individuals with sub-threshold symptomatology (van Zoonen et al., 2014).
In a new large randomised controlled trial (RCT) published yesterday in JAMA, Buntrock and co-authors investigated whether a web-based guided self-help intervention could help prevent the onset of major depressive disorder (MDD) in a German adult population with sub-threshold depression.
A. for Healthcare Research, and Q. (US) (Eds.) (December 2009)Rockville (MD): Agency for Healthcare Research and Quality (US); 2009 Dec. Report No.: 10-05143-EF-1. U.S. Preventive Services Task Force Evidence Syntheses, formerly Systematic Evidence Reviews.PMID: 20722174.
T. Itatsu, A. Nagahara, M. Hojo, A. Miyazaki, T. Murai, M. Nakajima, and S. Watanabe. Internal medicine (Tokyo, Japan), 50 (7):
713-7(January 2011)JID: 9204241; 0 (Serotonin Uptake Inhibitors); 2011/04/01 epublish; ppublish; Confusió absoluta entre cas-control i exposats-no exposats<br/><br/><br/>Tipus d'estudis.