Although in many cases the cause of anemia is not found, a primary deficiency of erythropoietin may be at fault in at least some of these cases since the response of erythropoietin to anemia may decrease in individuals over age 70. Conclusions: Anemia sh
Aging may be an intrinsic factor in the development of anemia, possibly through the age-related dysregulation of certain proinflammatory cytokines such as interleukin-6 (IL-6)...Increased IL-6 and other proinflammatory cytokines directly inhibit erythropo
S. Engelhardt, L. Hein, F. Wiesmann, and M. Lohse. Proc Natl Acad Sci U S A, 96 (12):
7059-64(June 1999)Engelhardt, S Hein, L Wiesmann, F Lohse, M J Research Support, Non-U.S.
Gov't United states Proceedings of the National Academy of Sciences
of the United States of America Proc Natl Acad Sci U S A. 1999 Jun
8;96(12):7059-64..