By focusing on well-known examples, Goodall, through his compelling writing style, points to easily identifiable signposts that trapped “great” men. The profiles in Why Great Men Fall give pause to others in similar environments: corporate execs, mini
A single protein in the brain influences arousal of despair, according to new study in mice. Brain biopsies revealed that mice trying hardest to escape shocks had highest levels of delta-FosB - which may also help humans avoid hopelessness & helplessness.
Modafinil induces wakefulness, but its dopamine-releasing action in the nucleus accumbens is weak and dose-dependent; no likelihood of euphoric response ('abuse potential').
Weak willpower & procrastination caused by dopamine hypofunction is one of those neurological deficiencies which effort alone can't overcome. Happily, in our transhuman paradise, even the most lethargic spirit can move mountains.
The social avoidance that normally develops when a mouse repeatedly experiences defeat by a dominant animal disappears when it lacks a gene for a memory molecule in a brain circuit for social learning, scientists funded by the National Institutes of Healt
Authorities report that more than half the population experiences trauma, which makes people more likely to develop PTSD, depression, anxiety and physical illness later in life. Now, a new study finds that among ‘healthy’ individuals, those who displa
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ABSTRACT FROM: Maselko J, Sikander S, Bhalotra S, et al. Effect of an early perinatal depression intervention on long-term child development outcomes: follow-up of the Thinking Healthy Programme randomised controlled trial. Lancet Psychiatry 2015;2:609–17. To read the full commentary, log in using your NHS OpenAthens details
Objective To identify information priorities for consumers and clinicians making depression treatment decisions and assess shared decision-making (SDM) in routine depression care. Open Access Article