Researchers say circulating mononuclear cells (the largest type of white blood cell) and lymphocytes, exist in a proinflammatory state in obese persons known to be at increased risk of developing heart disease, diabetes, or both.
The cellular and extracellular matrix accumulations that comprise the lesions of atherosclerosis are driven by local release of cytokines at sites of predilection for lesion formation, and by the specific attraction and activation of cells expressing rece
Angiographic pattern of in-stent restenosis (ISR) after drug-eluting stent (DES) implantation different to that after bare metal stent (BMS), but their subsequent TLR rate was similar to both types of DES.
Drug-eluting stents (DES) have gained widespread adoption being implanted in over 6 million patients worldwide demonstrating significant improvements in clinical efficacy combined with comparable safety to bare metal stents.
Modern cardiology has given up on curing heart disease. Its aggressive interventions-- coronary artery bypass graft, atherectomy, angioplasty, and stenting--do not reduce the frequency of new heart attacks or prolong survival except in small subsets of pa
it may no longer be enough to measure just HDL levels without determining levels of paroxonase and platelet-activating acetylhydrolase; levels of these enzymes may determine whether HDL is proinflammatory or protective. Likewise, measuring Lp(a) and small
For "traditional" cardiologists, CAD is a blockage or blockages in the coronary arteries, and the treatment is stents. For "nontraditional" cardiologists, CAD is a more systemic, diffuse condition, and the treatment is systemic.
Anti-Inflammatory Effects of Pioglitazone and/or Simvastatin in High Cardiovascular Risk Patients With Elevated High Sensitivity C-Reactive Protein The PIOSTAT Study
While the cause of statin-associated myopathy is controversial, a central role for coenzyme Q10 (CoQ10 or ubiquinone) is slowly gaining acceptance. Statins have been shown to create an acquired CoQ10 deficiency.
ntake of Fish Oil, Oleic Acid, Folic Acid, and Vitamins B-6 and E for 1 Year Decreases Plasma C-Reactive Protein and Reduces Coronary Heart Disease Risk Factors in Male Patients in a Cardiac Rehabilitation Program1
Ex: Managing the Metric vs Managing the Patient: The Physician’s View of Pay for Performance, Inpatient Management Guidelines for People with Diabetes, Reducing Health Care Costs for Plan Members with Congestive Heart Failure...
Chronic inflammation is also involved in diseases as diverse as atherosclerosis, cancer, heart valve dysfunction, obesity, diabetes, congestive heart failure, digestive system diseases, and Alzheimer's disease...The New England Journal of Medicine publish
[free after 18 months, from 1965] The Journal of Wildlife Diseases publishes the results of original research and observations dealing with all aspects of infectious, parasitic, toxic, nutritional, physiologic, developmental and neoplastic diseases, environmental contamination, and other factors impinging on the health and survival of free-living or captive populations of wild animals, including fish. Papers on zoonoses involving wildlife and on chemical immobilization of wild animals are published also. Manuscripts dealing with surveys and case reports may be published in the Journal provided that they contain significant new information or have significance for better understanding health and disease in wild populations. Authors are encouraged to address the wildlife management implications of their studies, where appropriate.
Free or low-cost sources of unstructured information, such as Internet news and online discussion sites, provide detailed local and near real-time data on disease outbreaks, even in countries that lack traditional public health surveillance. To improve public health surveillance and, ultimately, interventions, we examined 3 primary systems that process event-based outbreak information: Global Public Health Intelligence Network, HealthMap, and EpiSPIDER. Despite similarities among them, these systems are highly complementary because they monitor different data types, rely on varying levels of automation and human analysis, and distribute distinct information. Future development should focus on linking these systems more closely to public health practitioners in the field and establishing collaborative networks for alert verification and dissemination. Such development would further establish event-based monitoring as an invaluable public health resource that provides critical context and an alternative to traditional indicator-based outbreak reporting.
Scientists have uncovered a chain reaction which could link Enterococcus faecalis bacteria living in our intestines to the development of colon cancer.
India, Bangladesh, Vietnam and mainland China also experienced new outbreaks of H5 N1 influenza in December. During the same period, four new human cases - in Egypt, Cambodia and Indonesia - were reported to the World Health Organization. A 16-year-old girl in Egypt and a 2-year-old girl in Indonesia have died.
Health care workers in emergency departments are often carriers of the methicillin-resistant Staphylococcus aureus (MRSA), potentially putting patients at risk.
An outbreak of Q Fever is being investigated in the Cheltenham area. A total of 28 cases have been identified among local people, most requiring hospital treatment.
A hunt is on for 2 patients with a deadly form of tuberculosis who disappeared after the Cape High Court ordered they return to a South African hospital. The pair, diagnosed with extremely drug resistant (XDR) tuberculosis, are presumed to be in hiding.
There is seemingly consistent and compelling evidence that there is no association between breastfeeding and breast cancer. We challenge the assumption follows that milk borne viruses cannot be associated with human breast cancer.
Scientists are no further forward in developing a vaccine against HIV after more than 20 years of research says Nobel Prize-winning biologist David Baltimore.
The 1918 influenza strain developed two mutations in the hemagglutinin which allowed it to bind tightly to receptors in the human upper respiratory tract.
Ciguatera poisoning is caused by the consumption of tropical reef fish that have assimilated ciguatoxins through the marine food chain from toxic microscopic algae.
While individual prizes can encourage research in specific areas, they cannot address the wider problem of high drug prices. The cost of new medicines has skyrocketed in the past 20 years
In a 13-month period in the UK there were six deaths and 112 cases of severe complications among children. Vaccinating all children is the only way to prevent severe illness and death from chickenpox.
As of 28 March, 2008, the Brazilian health authorities have reported a national total of 120,570 cases of dengue including 647 dengue haemorrhagic fever (DHF) cases, with 48 deaths.
