As the study showed, experiencing auditory hallucinations was linked to poorer well-being in dementia. This suggests that auditory hallucinations should be targeted by appropriate treatments when aiming to improve well-being in people living with the condition.
The Comprehensive Process Model of Group Engagement posits that personal factors (e.g., cognitive function), stimulus factors (e.g., group activity content, group size) and environmental factors (e.g., light, noise) impact the response to group activities. This paper reports the impact of environmental and group characteristics on engagement, mood, and sleepiness of persons with dementia attending group activities.. To read the full article, log in using your MPFT NHS OpenAthens details.
Worldwide, life expectancy and ageing‐related disorders as Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) are increasing, having a rising impact on patients’ quality of life and caregivers’ distress. Telemedicine offers many possibilities, such as remote diagnosing and monitoring patients.. To read the full article, log in using your MPFT NHS OpenAthens details.
To explore the complexities, circumstances, and range of services commissioned for people with dementia living at home.. To read the full article, log in using your MPFT NHS OpenAthens details.
To study the frequency of suicidal ideation and its association with clinical and neurobiological correlates among cognitively intact autosomal dominant Alzheimer's disease (ADAD) at‐risk individuals.. To read the full article, log in using your MPFT NHS OpenAthens details.
In the UK, an estimated 954 000 people have dementia. Lewy body dementia (LBD) can be difficult to diagnose and estimates of its prevalence in the UK range from 38 000–100 000 (Prince et al, 2014:14, 16; Table 4, 2019 estimates; NHS, 2019).
This article, the fourth in a series, explains about the pathophysiology and clinical features of LBD, how it is diagnosed, treated and managed. To read the full article, log in using your MPFT NHS OpenAthens details.
On 21 June 2019 the House of Commons Library published a briefing paper entitled Dementia: Policy, services and statistics, which reviews the policies, services and statistical evidence pertinent to people living with dementia in England (Powell and Baker, 2019).
This parliamentary briefing gives details of several campaigns and policies on dementia care in the UK, one of which is the campaign led by the Alzheimer's Society entitled ‘Fix Dementia Care’. This campaign calls for the state to play a larger role in underwriting the costs of dementia care. To read the full article, log in using your MPFT NHS OpenAthens details.
A study investigating the link between gum disease bacteria and Alzheimer's disease has found compelling correlational evidence, with implications for treatment. To read the full article, log in using your MPFT NHS OpenAthens details.
A major contributor to dementia in Parkinson disease (PD) is degeneration of the cholinergic basal forebrain. This study determined whether cholinergic nucleus 4 (Ch4) density is associated with cognition in early and more advanced PD.. To read the full article, log in using your NHS OpenAthens details.
Free access. Dementia is a common, debilitating feature of late Parkinson’s disease (PD). PD dementia (PDD) is associated with α-synuclein propagation, but coexistent Alzheimer’s disease (AD) pathology may coexist. Other pathologies (cerebrovascular, transactive response DNA-binding protein 43 (TDP-43)) may also influence cognition. We aimed to describe the neuropathology underlying dementia in PD.
Open access. Traumatic brain injury (TBI) leads to increased rates of dementia, including Alzheimer’s disease. The mechanisms by which trauma can trigger neurodegeneration are increasingly understood. For example, diffuse axonal injury is implicated in disrupting microtubule function, providing the potential context for pathologies of tau and amyloid to develop. The neuropathology of post-traumatic dementias is increasingly well characterised, with recent work focusing on chronic traumatic encephalopathy (CTE). However, clinical diagnosis of post-traumatic dementia is problematic. It is often difficult to disentangle the direct effects of TBI from those produced by progressive neurodegeneration or other post-traumatic sequelae such as psychiatric impairment. CTE can only be confidently identified at postmortem and patients are often confused and anxious about the most likely cause of their post-traumatic problems.
Multimodal MRI-based classification may aid early frontotemporal dementia (FTD) diagnosis. Recently, presymptomatic FTD mutation carriers, who have a high risk of developing FTD, were separated beyond chance level from controls using MRI-based classification. However, it is currently unknown how these scores from classification models progress as mutation carriers approach symptom onset. In this longitudinal study, we investigated multimodal MRI-based classification scores between presymptomatic FTD mutation carriers and controls. Furthermore, we contrasted carriers that converted during follow-up (‘converters’) and non-converting carriers (‘non-converters’).. To read the full article, log in using your NHS OpenAthens details.
Nurse specialists have helped create a dementia-friendly X-ray room with woodland imagery and music tailored to each patient. To read the full article, log in using your MPFT NHS OpenAthens details.
A new dementia app could prove a vital tool in supporting patients and families from black and minority ethnic (BME) communities, according to a leading nurse. To read the full article, log in using your MPFT NHS OpenAthens details.
Older lesbian, gay, bisexual, trans, queer and others (LGBTQ+) people living with dementia have specific needs related to their sexual orientation and identity that should be addressed to maintain their personhood. They may face challenges in health and social care settings, such as heteronormativity and lack of awareness of older LGBTQ+ needs. Service provision for older LGBTQ+ people with dementia is lacking. Healthcare professionals’ attitudes towards older LGBTQ+ people with dementia are often poor and there is a clear need for better training, while increased knowledge and awareness would help to challenge the concept of heteronormativity. To read the full article, log in using your MPFT NHS OpenAthens details.
While these initial results are interesting for researchers, this treatment is still in the experimental stages. Further study in more people is needed to ensure that it causes no long-term harm and to get a better idea of what impact it could have on clinical outcomes in a wider setting.
Hence we're still some way off from knowing whether this really is a breakthrough in AD treatment.
F. Molnar, B. Hutton, and D. Fergusson. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 179 (8):
751-3(October 2008)4563<br/>PUBM: Print; JID: 9711805; ppublish;<br/>Dades censurades; LOCF; Bias.