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Protein kinase cross-talk: membrane targeting of the beta-adrenergic receptor kinase by protein kinase C
R. Winstel, S. Freund, C. Krasel, E. Hoppe, and M. J. Lohse. Proc Natl Acad Sci U S A 93(5):2105-9 (March 1996)Winstel, R Freund, S Krasel, C Hoppe, E Lohse, M J Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1996 Mar 5;935:2105-9..
R. Winstel, S. Freund, C. Krasel, E. Hoppe, and M. J. Lohse. Proc Natl Acad Sci U S A 93(5):2105-9 (March 1996)Winstel, R Freund, S Krasel, C Hoppe, E Lohse, M J Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1996 Mar 5;935:2105-9..
2 years and 5 months ago
by pharmawuerz
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AMP-Dependent Acid Activation/drug Amino Animals C/*physiology CHO Cell Compartmentation Cricetinae Cyclic Data Enzyme Epinephrine/pharmacology Humans Kinase Kinases Kinases/*metabolism Line Membrane/enzymology Molecular Peptides/chemistry Phosphorylation Protein Proteins Receptor Recombinant Sequence Signal Transduction alpha-1/*metabolism beta-Adrenergic effects Adrenergic
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Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart
M. Ungerer, G. Parruti, M. Bohm, M. Puzicha, A. DeBlasi, E. Erdmann, and M. J. Lohse. Circ Res 74(2):206-13 (February 1994)Ungerer, M Parruti, G Bohm, M Puzicha, M DeBlasi, A Erdmann, E Lohse, M J Research Support, Non-U.S. Gov't United states Circulation research Circ Res. 1994 Feb;742:206-13..
M. Ungerer, G. Parruti, M. Bohm, M. Puzicha, A. DeBlasi, E. Erdmann, and M. J. Lohse. Circ Res 74(2):206-13 (February 1994)Ungerer, M Parruti, G Bohm, M Puzicha, M DeBlasi, A Erdmann, E Lohse, M J Research Support, Non-U.S. Gov't United states Circulation research Circ Res. 1994 Feb;742:206-13..
2 years and 5 months ago
by pharmawuerz
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*Arrestins AMP-Dependent Acid Adult Aged Amino Antigens/genetics/*metabolism Blotting, Cardiac Chain Cyclic Data Eye Female Fragments/genetics Genetic Humans Isomerism Kinases Kinases/genetics/*metabolism Low/*metabolism Male Messenger/metabolism Middle Molecular Myocardium/metabolism Output, Peptide Polymerase Protein Proteins/genetics/*metabolism RNA, Reaction Receptor Sequence Transcription, Western beta-Adrenergic
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Activation of beta-adrenergic receptor kinase during myocardial ischemia
M. Ungerer, K. Kessebohm, K. Kronsbein, M. J. Lohse, and G. Richardt. Circ Res 79(3):455-60 (September 1996)Ungerer, M Kessebohm, K Kronsbein, K Lohse, M J Richardt, G In Vitro Research Support, Non-U.S. Gov't United states Circulation research Circ Res. 1996 Sep;793:455-60..
M. Ungerer, K. Kessebohm, K. Kronsbein, M. J. Lohse, and G. Richardt. Circ Res 79(3):455-60 (September 1996)Ungerer, M Kessebohm, K Kronsbein, K Lohse, M J Richardt, G In Vitro Research Support, Non-U.S. Gov't United states Circulation research Circ Res. 1996 Sep;793:455-60..
2 years and 5 months ago
by pharmawuerz
2
*Arrestins AMP-Dependent Animals Base Cyclic Data Eye Ischemia/*metabolism Kinases Kinases/genetics/*metabolism Male Messenger/metabolism Molecular Myocardial Probes Protein Proteins/metabolism RNA, Rats Receptor Sequence Wistar beta-Adrenergic beta/metabolism Adrenergic
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Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart
M. Ungerer, M. Bohm, J. S. Elce, E. Erdmann, and M. J. Lohse. Circulation 87(2):454-63 (February 1993)Ungerer, M Bohm, M Elce, J S Erdmann, E Lohse, M J In Vitro Research Support, Non-U.S. Gov't United states Circulation Circulation. 1993 Feb;872:454-63..
M. Ungerer, M. Bohm, J. S. Elce, E. Erdmann, and M. J. Lohse. Circulation 87(2):454-63 (February 1993)Ungerer, M Bohm, M Elce, J S Erdmann, E Lohse, M J In Vitro Research Support, Non-U.S. Gov't United states Circulation Circulation. 1993 Feb;872:454-63..
2 years and 5 months ago
by pharmawuerz
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*Cyclic AMP-Dependent Adult Aged Base Binding, Calcium/pharmacology Cardiac Cardiomyopathy, Chain Competitive Contraction/drug Coronary Data Dilated/metabolism Disease/metabolism Electric Female Forskolin/pharmacology Humans Isoproterenol/pharmacology Kinases Kinases/genetics/*metabolism Low/*metabolism/physiopathology Male Messenger/metabolism Middle Molecular Muscles/drug Myocardial Oligonucleotide Output, Papillary Polymerase Probes/genetics Protein RNA, Reaction Receptor Sequence Stimulation beta-Adrenergic beta/genetics/metabolism effects Adrenergic
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Binding of purified recombinant beta-arrestin to guanine-nucleotide-binding-protein-coupled receptors
P. Sohlemann, M. Hekman, M. Puzicha, C. Buchen, and M. J. Lohse. Eur J Biochem 232(2):464-72 (September 1995)Sohlemann, P Hekman, M Puzicha, M Buchen, C Lohse, M J Research Support, Non-U.S. Gov't Germany European journal of biochemistry / FEBS Eur J Biochem. 1995 Sep 1;2322:464-72..
P. Sohlemann, M. Hekman, M. Puzicha, C. Buchen, and M. J. Lohse. Eur J Biochem 232(2):464-72 (September 1995)Sohlemann, P Hekman, M Puzicha, M Buchen, C Lohse, M J Research Support, Non-U.S. Gov't Germany European journal of biochemistry / FEBS Eur J Biochem. 1995 Sep 1;2322:464-72..
2 years and 5 months ago
by pharmawuerz
1
*Arrestins AMP-Dependent Adenylate Animals Antigens/genetics/*metabolism Binding Cell Cyclase/metabolism Cyclic Expression Eye GTP-Binding Gene Humans Kinases Kinases/metabolism Kinetics Line Outer Phosphorylation Protein Proteins/genetics/*metabolism Proteins/genetics/metabolism Receptor Recombinant Rhodopsin/metabolism Rod Segment/metabolism Spodoptera beta-2/chemistry/genetics/*metabolism beta-Adrenergic Proteins/metabolism Adrenergic
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Purification and functional characterization of beta-adrenergic receptor kinase expressed in insect cells
P. Sohlemann, M. Hekman, C. Buchen, J. S. Elce, and M. J. Lohse. FEBS Lett 324(1):59-62 (June 1993)Sohlemann, P Hekman, M Buchen, C Elce, J S Lohse, M J Comparative Study Research Support, Non-U.S. Gov't Netherlands FEBS letters FEBS Lett. 1993 Jun 7;3241:59-62..
P. Sohlemann, M. Hekman, C. Buchen, J. S. Elce, and M. J. Lohse. FEBS Lett 324(1):59-62 (June 1993)Sohlemann, P Hekman, M Buchen, C Elce, J S Lohse, M J Comparative Study Research Support, Non-U.S. Gov't Netherlands FEBS letters FEBS Lett. 1993 Jun 7;3241:59-62..
2 years and 5 months ago
by pharmawuerz
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& *Cyclic AMP-Dependent Adenosine Animals Cell Chromatography, Cloning, Exchange Gel Humans Ion Kinases Kinases/genetics/*isolation Kinetics Line Molecular Moths Outer Phosphorylation Protein Proteins/isolation Receptor Recombinant Rhodopsin/metabolism Rod Segment/metabolism Transfection Triphosphate/metabolism beta-Adrenergic purification/*metabolism purification/metabolism
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Expression of phosducin in a phosducin-negative cell line reveals functions of a Gbetagamma-binding protein
K. Schulz, S. Danner, P. Bauer, S. Schroder, and M. J. Lohse. J Biol Chem 271(37):22546-51 (September 1996)Schulz, K Danner, S Bauer, P Schroder, S Lohse, M J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1996 Sep 13;27137:22546-51..
K. Schulz, S. Danner, P. Bauer, S. Schroder, and M. J. Lohse. J Biol Chem 271(37):22546-51 (September 1996)Schulz, K Danner, S Bauer, P Schroder, S Lohse, M J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1996 Sep 13;27137:22546-51..
2 years and 5 months ago
by pharmawuerz
1
& 1-Methyl-3-isobutylxanthine/pharmacology AMP-Dependent AMP/metabolism Acid Adenylate Adrenergic Amino Blotting, Cell Cyclase/metabolism Cyclic Data Eye GTP-Binding Humans Inhibitors/pharmacology Isoproterenol/pharmacology Kinases/antagonists Line Molecular Phosphodiesterase Phosphoproteins/*biosynthesis Protein Proteins/*biosynthesis Regulators Sequence Signal Transduction Transfection Western beta-Agonists/pharmacology beta/metabolism inhibitors Receptor Proteins/metabolism
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Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban
J. P. Schmitt, M. Kamisago, M. Asahi, G. H. Li, F. Ahmad, U. Mende, E. G. Kranias, D. H. MacLennan, J. G. Seidman, and C. E. Seidman. Science 299(5611):1410-3 (February 2003)Schmitt, Joachim P Kamisago, Mitsuhiro Asahi, Michio Li, Guo Hua Ahmad, Ferhaan Mende, Ulrike Kranias, Evangelia G MacLennan, David H Seidman, J G Seidman, Christine E Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States Science New York, N.Y. Science. 2003 Feb 28;2995611:1410-3..
J. P. Schmitt, M. Kamisago, M. Asahi, G. H. Li, F. Ahmad, U. Mende, E. G. Kranias, D. H. MacLennan, J. G. Seidman, and C. E. Seidman. Science 299(5611):1410-3 (February 2003)Schmitt, Joachim P Kamisago, Mitsuhiro Asahi, Michio Li, Guo Hua Ahmad, Ferhaan Mende, Ulrike Kranias, Evangelia G MacLennan, David H Seidman, J G Seidman, Christine E Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. United States Science New York, N.Y. Science. 2003 Feb 28;2995611:1410-3..
2 years and 5 months ago
by pharmawuerz
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& *Mutation, AMP-Dependent ATPases ATPases/antagonists Acid Amino Animals Calcium Calcium-Binding Calcium-Transporting Calcium/metabolism Cardiomegaly Cardiomyopathy, Cell Cells/metabolism/physiology Contraction Cyclic Data Dilated/*genetics/pathology/physiopathology Failure/*genetics/pathology/physiopathology Female Heart Humans Kinases/metabolism Line Lod Male Mice Missense Molecular Muscle Myocardial Myocardium/pathology Pedigree Phosphorylation Protein Proteins/chemistry/*genetics/*physiology Reticulum Sarcoplasmic Score Sequence Signaling Substitution Transgenic Ventricles/metabolism/pathology inhibitors/metabolism
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Phosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2
A. Ruiz-Gomez, J. Humrich, C. Murga, U. Quitterer, M. J. Lohse, and Jr. Mayor. J Biol Chem 275(38):29724-30 (September 2000)Ruiz-Gomez, A Humrich, J Murga, C Quitterer, U Lohse, M J Mayor, F Jr Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 2000 Sep 22;27538:29724-30..
A. Ruiz-Gomez, J. Humrich, C. Murga, U. Quitterer, M. J. Lohse, and Jr. Mayor. J Biol Chem 275(38):29724-30 (September 2000)Ruiz-Gomez, A Humrich, J Murga, C Quitterer, U Lohse, M J Mayor, F Jr Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 2000 Sep 22;27538:29724-30..
2 years and 5 months ago
by pharmawuerz
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*Signal 2 AMP-Dependent Animals Carrier Cell Cyclic Eye G-Protein-Coupled GTP-Binding Kinase Kinases Kinases/*metabolism Line Nerve Phosphoproteins/*metabolism Phosphorylation Protein Proteins Receptor Regulators Specificity Substrate Tissue Transduction beta-Adrenergic Proteins/metabolism
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Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase
N. S. Roth, P. T. Campbell, M. G. Caron, R. J. Lefkowitz, and M. J. Lohse. Proc Natl Acad Sci U S A 88(14):6201-4 (July 1991)Roth, N S Campbell, P T Caron, M G Lefkowitz, R J Lohse, M J HL16037/HL/NHLBI NIH HHS/United States Comparative Study Research Support, U.S. Gov't, P.H.S. United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1991 Jul 15;8814:6201-4..
N. S. Roth, P. T. Campbell, M. G. Caron, R. J. Lefkowitz, and M. J. Lohse. Proc Natl Acad Sci U S A 88(14):6201-4 (July 1991)Roth, N S Campbell, P T Caron, M G Lefkowitz, R J Lohse, M J HL16037/HL/NHLBI NIH HHS/United States Comparative Study Research Support, U.S. Gov't, P.H.S. United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1991 Jul 15;8814:6201-4..
2 years and 5 months ago
by pharmawuerz
1
*Cyclic A/pharmacology AMP-Dependent Carcinoma, Cell Concanavalin GTP-Binding Humans Isoproterenol/*pharmacology Kinases Kinases/*metabolism Kinetics Line Membrane Permeability Protein Proteins/metabolism Receptor Squamous beta-Adrenergic beta/drug effects/*metabolism Adrenergic
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Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms
J. Pitcher, M. J. Lohse, J. Codina, M. G. Caron, and R. J. Lefkowitz. Biochemistry 31(12):3193-7 (March 1992)Pitcher, J Lohse, M J Codina, J Caron, M G Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, U.S. Gov't, P.H.S. United states Biochemistry Biochemistry. 1992 Mar 31;3112:3193-7..
J. Pitcher, M. J. Lohse, J. Codina, M. G. Caron, and R. J. Lefkowitz. Biochemistry 31(12):3193-7 (March 1992)Pitcher, J Lohse, M J Codina, J Caron, M G Lefkowitz, R J HL16037/HL/NHLBI NIH HHS/United States Research Support, U.S. Gov't, P.H.S. United states Biochemistry Biochemistry. 1992 Mar 31;3112:3193-7..
2 years and 5 months ago
by pharmawuerz
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& *Cyclic AMP-Dependent AMP/physiology Adrenergic Animals Antigens/physiology Arrestin C/*pharmacology Cricetinae Cyclic Drug Eye Humans Kinase Kinases Kinases/*pharmacology Lung/chemistry Phosphorylation Protein Proteins/physiology Receptor Retina/chemistry Synergism beta-Adrenergic beta-Agonists/*pharmacology beta/*drug effects/isolation purification
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Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization
S. Pippig, S. Andexinger, and M. J. Lohse. Mol Pharmacol 47(4):666-76 (April 1995)Pippig, S Andexinger, S Lohse, M J Research Support, Non-U.S. Gov't United states Molecular pharmacology Mol Pharmacol. 1995 Apr;474:666-76..
S. Pippig, S. Andexinger, and M. J. Lohse. Mol Pharmacol 47(4):666-76 (April 1995)Pippig, S Andexinger, S Lohse, M J Research Support, Non-U.S. Gov't United states Molecular pharmacology Mol Pharmacol. 1995 Apr;474:666-76..
2 years and 5 months ago
by pharmawuerz
2
AMP-Dependent Cultured Cyclic Humans Kinases Kinases/physiology Monensin/pharmacology Oxazoles/pharmacology Phosphorylation Protein Receptor Sucrose/pharmacology Tumor beta-2/*metabolism beta-Adrenergic Cell Adrenergic
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Overexpression of beta-arrestin and beta-adrenergic receptor kinase augment desensitization of beta 2-adrenergic receptors
S. Pippig, S. Andexinger, K. Daniel, M. Puzicha, M. G. Caron, R. J. Lefkowitz, and M. J. Lohse. J Biol Chem 268(5):3201-8 (February 1993)Pippig, S Andexinger, S Daniel, K Puzicha, M Caron, M G Lefkowitz, R J Lohse, M J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1993 Feb 15;2685:3201-8..
S. Pippig, S. Andexinger, K. Daniel, M. Puzicha, M. G. Caron, R. J. Lefkowitz, and M. J. Lohse. J Biol Chem 268(5):3201-8 (February 1993)Pippig, S Andexinger, S Daniel, K Puzicha, M Caron, M G Lefkowitz, R J Lohse, M J Research Support, Non-U.S. Gov't United states The Journal of biological chemistry J Biol Chem. 1993 Feb 15;2685:3201-8..
2 years and 5 months ago
by pharmawuerz
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& *Arrestins *Cyclic 5'-O-(3-Thiotriphosphate)/pharmacology AMP-Dependent Acid Adenylate Amino Animals Antibodies Antigens/genetics/*metabolism Blotting, CHO Cell Chloride/pharmacology Cricetinae Cyclase/metabolism Data Eye GTP Guanosine Iodine Iodocyanopindolol Isoproterenol/*pharmacology Kinases Kinases/genetics/*metabolism Kinetics Line Magnesium Molecular Peptides/chemical Phosphohydrolases/metabolism Phosphorus Pindolol/analogs Protein Proteins/genetics/*metabolism Radioisotopes Radioisotopes/metabolism Receptor Sequence Transfection Western beta-Adrenergic beta/*drug derivatives/metabolism effects/metabolism synthesis/immunology Adrenergic
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Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation
V. O. Nikolaev, A. Moshkov, A. R. Lyon, M. Miragoli, P. Novak, H. Paur, M. J. Lohse, Y. E. Korchev, S. E. Harding, and J. Gorelik. Science 327(5973):1653-7 (March 2010)Nikolaev, Viacheslav O Moshkov, Alexey Lyon, Alexander R Miragoli, Michele Novak, Pavel Paur, Helen Lohse, Martin J Korchev, Yuri E Harding, Sian E Gorelik, Julia 084064/Wellcome Trust/United Kingdom Biotechnology and Biological Sciences Research Council/United Kingdom Medical Research Council/United Kingdom Research Support, Non-U.S. Gov't United States Science New York, N.Y. Science. 2010 Mar 26;3275973:1653-7. Epub 2010 Feb 25..
V. O. Nikolaev, A. Moshkov, A. R. Lyon, M. Miragoli, P. Novak, H. Paur, M. J. Lohse, Y. E. Korchev, S. E. Harding, and J. Gorelik. Science 327(5973):1653-7 (March 2010)Nikolaev, Viacheslav O Moshkov, Alexey Lyon, Alexander R Miragoli, Michele Novak, Pavel Paur, Helen Lohse, Martin J Korchev, Yuri E Harding, Sian E Gorelik, Julia 084064/Wellcome Trust/United Kingdom Biotechnology and Biological Sciences Research Council/United Kingdom Medical Research Council/United Kingdom Research Support, Non-U.S. Gov't United States Science New York, N.Y. Science. 2010 Mar 26;3275973:1653-7. Epub 2010 Feb 25..
2 years and 5 months ago
by pharmawuerz
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AMP-Dependent AMP/*metabolism Animals Cardiac/*metabolism/ultrastructure Cell Chronic Compartmentation Cyclic Cytosol/metabolism Disease Energy Failure/*metabolism/*pathology Fluorescence Heart Kinases/metabolism Knockout Male Membrane/*metabolism/ultrastructure Mice Microscopy/methods Myocytes, Protein Rats Resonance Sarcolemma/*metabolism/ultrastructure Signal Sprague-Dawley Transduction Transfer Transgenic beta-1/genetics/metabolism beta-2/genetics/*metabolism Receptor Adrenergic
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Monitoring of cAMP synthesis and degradation in living cells
V. O. Nikolaev, and M. J. Lohse. Physiology Bethesda (April 2006)Nikolaev, Viacheslav O Lohse, Martin J Review United States Physiology Bethesda, Md. Physiology Bethesda. 2006 Apr;21:86-92..
V. O. Nikolaev, and M. J. Lohse. Physiology Bethesda (April 2006)Nikolaev, Viacheslav O Lohse, Martin J Review United States Physiology Bethesda, Md. Physiology Bethesda. 2006 Apr;21:86-92..
2 years and 5 months ago
by pharmawuerz
2
AMP-Dependent AMP/analysis/*metabolism Animals Antiporters/physiology Biosensing Calcium/physiology Cation Cells/chemistry/*metabolism Channels Channels/physiology Cyclic Cytosol/chemistry Electrophysiology/*methods Exchange Factors/analysis/physiology Fluorescence/*methods Guanine Humans Hydrolysis Ion Kinases/physiology Microscopy, Nucleotide Nucleotide-Gated Protein Radioimmunoassay Techniques
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Selectivity of beta-adrenergic receptor kinase 2 for G protein betagamma subunits
S. Muller, A. Straub, and M. J. Lohse. FEBS Lett 401(1):25-9 (January 1997)Muller, S Straub, A Lohse, M J Research Support, Non-U.S. Gov't Netherlands FEBS letters FEBS Lett. 1997 Jan 13;4011:25-9..
S. Muller, A. Straub, and M. J. Lohse. FEBS Lett 401(1):25-9 (January 1997)Muller, S Straub, A Lohse, M J Research Support, Non-U.S. Gov't Netherlands FEBS letters FEBS Lett. 1997 Jan 13;4011:25-9..
2 years and 5 months ago
by pharmawuerz
2
AMP-Dependent Animals Cyclic GTP-Binding Isoenzymes/*metabolism Kinases Kinases/*metabolism Phosphorylation Protein Proteins/metabolism Receptor Recombinant Rhodopsin/metabolism Specificity Substrate beta-Adrenergic
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Specific enhancement of beta-adrenergic receptor kinase activity by defined G-protein beta and gamma subunits
S. Muller, M. Hekman, and M. J. Lohse. Proc Natl Acad Sci U S A 90(22):10439-43 (November 1993)Muller, S Hekman, M Lohse, M J In Vitro Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1993 Nov 15;9022:10439-43..
S. Muller, M. Hekman, and M. J. Lohse. Proc Natl Acad Sci U S A 90(22):10439-43 (November 1993)Muller, S Hekman, M Lohse, M J In Vitro Research Support, Non-U.S. Gov't United states Proceedings of the National Academy of Sciences of the United States of America Proc Natl Acad Sci U S A. 1993 Nov 15;9022:10439-43..
2 years and 5 months ago
by pharmawuerz
2
AMP-Dependent Activation Animals Baculoviridae Bordetella/pharmacology Cyclic Enzyme Factors, GTP-Binding Kinases Kinases/*metabolism Moths Phosphoproteins/metabolism Protein Proteins/metabolism Receptor Recombinant Rhodopsin/metabolism Virulence beta-Adrenergic beta/*metabolism Adrenergic
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Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells
S. Merighi, P. Mirandola, D. Milani, K. Varani, S. Gessi, K. N. Klotz, E. Leung, P. G. Baraldi, and P. A. Borea. J Invest Dermatol 119(4):923-33 (October 2002)Merighi, Stefania Mirandola, Prisco Milani, Daniela Varani, Katia Gessi, Stefania Klotz, Karl-Norbert Leung, Edward Baraldi, Pier Giovanni Borea, Pier Andrea United States The Journal of investigative dermatology J Invest Dermatol. 2002 Oct;1194:923-33..
S. Merighi, P. Mirandola, D. Milani, K. Varani, S. Gessi, K. N. Klotz, E. Leung, P. G. Baraldi, and P. A. Borea. J Invest Dermatol 119(4):923-33 (October 2002)Merighi, Stefania Mirandola, Prisco Milani, Daniela Varani, Katia Gessi, Stefania Klotz, Karl-Norbert Leung, Edward Baraldi, Pier Giovanni Borea, Pier Andrea United States The Journal of investigative dermatology J Invest Dermatol. 2002 Oct;1194:923-33..
2 years and 5 months ago
by pharmawuerz
2
1/metabolism 3 A2A A3 AMP-Dependent Activation Adenosine Adenosine/pharmacology Animals Apoptosis/*physiology C/physiology CHO Cell Cricetinae Cultured Cyclic Division Enzyme Humans Kinase Kinases/metabolism Kinases/physiology Melanoma/*pathology Mitogen-Activated P1/*physiology Protein Purinergic Tumor Receptor
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Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2
K. Lorenz, M. J. Lohse, and U. Quitterer. Nature 426(6966):574-9 (December 2003)Lorenz, Kristina Lohse, Martin J Quitterer, Ursula Research Support, Non-U.S. Gov't England Nature Nature. 2003 Dec 4;4266966:574-9..
K. Lorenz, M. J. Lohse, and U. Quitterer. Nature 426(6966):574-9 (December 2003)Lorenz, Kristina Lohse, Martin J Quitterer, Ursula Research Support, Non-U.S. Gov't England Nature Nature. 2003 Dec 4;4266966:574-9..
2 years and 5 months ago
by pharmawuerz
2
& *Androgen-Binding 2 3 AMP-Dependent Animals Binding Brain/metabolism C/*metabolism Cardiac/metabolism Carrier Cell Cyclic Enzyme G-Protein-Coupled Humans Inhibitors/*metabolism Interference Kinase Kinases Kinases/*antagonists Line Mice Myocytes, Phosphatidylethanolamine Phospholipid Phosphorylation Precipitin Protein Proteins Proteins/genetics/*metabolism Proto-Oncogene RNA Rats Receptor Signal Specificity Substrate Tests Transduction Transfer Uteroglobin beta-Adrenergic c-raf/*antagonists inhibitors/genetics/metabolism
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What is the role of beta-adrenergic signaling in heart failure?
M. J. Lohse, S. Engelhardt, and T. Eschenhagen. Circ Res 93(10):896-906 (November 2003)Lohse, Martin J Engelhardt, Stefan Eschenhagen, Thomas Review United States Circulation research Circ Res. 2003 Nov 14;9310:896-906..
M. J. Lohse, S. Engelhardt, and T. Eschenhagen. Circ Res 93(10):896-906 (November 2003)Lohse, Martin J Engelhardt, Stefan Eschenhagen, Thomas Review United States Circulation research Circ Res. 2003 Nov 14;9310:896-906..
2 years and 5 months ago
by pharmawuerz
2
*Signal AMP-Dependent Adrenergic Animal Animals Cyclic Disease Failure/drug GTP-Binding Heart Humans Kinases Kinases/metabolism Mice Models, Myocardium/*metabolism Protein Proteins/metabolism Receptor Transduction Transgenic beta-Adrenergic beta-Antagonists/therapeutic beta/genetics/*metabolism therapy/*physiopathology use
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