(Tramadol-warfarin interaction)
Drug and Therapeutics Bulletin 2024;62:36
https://doi.org/10.1136/dtb.2024.000008
Traducido por Salud y Fármacos, publicado en Boletín Fármacos: Farmacovigilancia 2024; 27 (2)
Tags: riesgo de hemorragia, anticoagulantes, tratamiento del dolor y riesgo de hemorragia
Resumen de: Danbury G Susan Gladstone: Informe sobre prevención de muertes futuras [en línea], 2023. Disponible: https://www.judiciary.uk/prevention-of-future-death-reports/susan-gladstone-prevention-offuture-deaths-report/ Consultado el 8 de enero de 2024].
Puntos más importantes
En el Reino Unido, los médicos forenses tienen la obligación de informar los casos en los que consideren que se deben tomar medidas para prevenir futuras muertes.
Un forense investigó el caso de una paciente que murió de hemorragia intraparenquimatosa y subaracnoidea.
La investigación concluyó que la causa de la hemorragia fue una interacción entre warfarina y tramadol que provocó un grado significativo de anticoagulación.
Un forense británico que concluyó que la muerte de una paciente se debió a una interacción generalmente desconocida entre la warfarina y el tramadol ha pedido a NHS (National Health Service o Servicio Nacional de Salud) de Inglaterra que tome medidas para prevenir futuras muertes por dicha interacción [1].
Extreme drought events have the potential to cause dramatic changes in ecosystem structure and function, but the controls upon ecosystem stability to drought remain poorly understood. Here we used model systems of two commonly occurring, temperate grassland communities to investigate the shortterm interactive effects of a simulated 100-year summer drought event, soil nitrogen (N) availability and plant species diversity (low/high) on key ecosystem processes related to carbon (C) and N cycling. Whole ecosystem CO2 fluxes and leaching losses were recorded during drought and post-rewetting. Litter decomposition and C/N stocks in vegetation, soil and soil microbes were assessed 4 weeks after the end of drought. Experimental drought caused strong reductions in ecosystem respiration and net ecosystem CO2 exchange, but ecosystem fluxes recovered rapidly following rewetting irrespective of N and species diversity. As expected, root C stocks and litter decomposition were adversely affected by drought across all N and plant diversity treatments. In contrast, drought increased soil water retention, organic nutrient leaching losses and soil fertility. Drought responses of above-ground vegetation C stocks varied depending on plant diversity, with greater stability of above-ground vegetation C to drought in the high versus low diversity treatment. This positive effect of high plant diversity on above-ground vegetation C stability coincided with a decrease in the stability of microbial biomass C. Unlike species diversity, soil N availability had limited effects on the stability of ecosystem processes to extreme drought. Overall, our findings indicate that extreme drought events promote post-drought soil nutrient retention and soil fertility, with cascading effects on ecosystem C fixation rates. Data on above-ground ecosystem processes underline the importance of species diversity for grassland function in a changing environment. Furthermore, our results suggest that plant–soil interactions play a key role for the short-term stability of above-ground vegetation C storage to extreme drought events.
The Experience API (xAPI) allows us to collect data about any type of learning experience or activity, but does that mean we should? Should we generate massive amounts of xAPI data for every possible type of interaction and then expect to make sense of it all later? This approach can be costly in terms of data storage, but also in terms of your time.
Sunday Blake dives into the latest in learning analytics and engagement data, and asks how universities can act upon it to make our interactions with students more human.
Dashboard is a prominent artefact that users interact with when it comes to learning analytics. What is a learning analytics dashboard ? Who is it for? What is the key to effective adoption of learning analytics dashboard? Listen to Martin Hlosta and Fabio Campos sharing their experience in supporting the use of learning analytics dashboard on a large scale.
Jon Udell on 21 JUL 2021
Suppose you're a member of a team that runs a public web service. You need to help both internal and external users make sense of all the data that's recorded as it runs. That's been my role for the past few years, now it's time to summarize what I've learned.
In this lecture series Bart Rienties (Professor of Learning Analytics, head of Academic Professional Development) will discuss how from the safety of your home you could use existing trace data to explore interactions between people (e.g., Twitter data, engagement data in a virtual learning environment, public data sets), and what the affordances and limitations of these trace data might be.
Trusted Learning Analytics beruhen auf vertrauensvollen Beziehungen zwischen Anwendern und Nutzern
FRAGEN AN (II/II) Hendrik Drachsler, Professor an der Goethe-Universität Frankfurt und Leiter des Arbeitsbereichs „Educational Technologies“ am DIPF | Leibniz-Institut für Bildungsforschung und Bildungsinformation, der sich nicht nur mit Bildungstechnologien auseinandersetzt, sondern auch daran arbeitet Learning Analytics an deutsche Hochschulen zu bringen.
This post is some thinking around Col's PhD resulting from some conversations and presentations from this year’s wonderful ALASI2018 conference held recently in Melbourne.
If you do research in the field of learning science there is almost certainly one point in which you realise how difficult is to model and describe a learning process.
Did you know that users are more likely to choose, buy and use products that meet their needs as opposed to products that just meet their wants? An Empathy map will help you understand your user’s needs while you develop a deeper understanding of the persons you are designing for. There are many techniques you can use to develop this kind of empathy. An Empathy Map is just one tool that can help you empathise and synthesise your observations from the research phase, and draw out unexpected insights about your user’s needs.
An Empathy Map allows us to sum up our learning from engagements with people in the field of design research. The map provides four major areas in which to focus our attention on, thus providing an overview of a person’s experience. Empathy maps are also great as a background for the construction of the personas that you would often want to create later.
An Empathy Map consists of four quadrants. The four quadrants reflect four key traits, which the user demonstrated/possessed during the observation/research stage. The four quadrants refer to what the user: Said, Did, Thought, and Felt. It’s fairly easy to determine what the user said and did. However, determining what they thought and felt should be based on careful observations and analysis as to how they behaved and responded to certain activities, suggestions, conversations, etc.
A flipped classroom approach to using video for igniting student discussion and engagement. Available on iOS, Android, Chromebook, and all major browsers.
B-2, Reading_2, Unit 1, Vygotsky, L.S. (1994 [1978]) ‘Interaction between learning and development’ in Stierer, B. and Maybin, J., (eds) Language, Literacy and Learning in Educational Practice, Clevedon, Multilingual Matters Limited.
J. Arzberger, J. Zevering, F. Arzberger, и A. Nüchter. Proceedings of the IEEE International Conference on Autonomous Robot Systems and Competitions (ICARSC '24), стр. 74--81. Paredes de Coura, Portugal, (2024)