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Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization
D. Fukumura, and R. K. Jain Microvasc.Res. 74(2-3):72-84 (2007)
to & Angiogenesis Animals Blood Endothelial Factors Growth Humans Inhibitors Laboratories Neoplasms Neovascularization Pathologic Research Vascular Vessels antagonists blood cells drug inhibitors pathology supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Sunitinib efficacy against advanced renal cell carcinoma
R. J. Motzer, M. D. Michaelson, J. Rosenberg, R. M. Bukowski, B. D. Curti, D. J. George, G. R. Hudes, B. G. Redman, K. A. Margolin, and G. Wilding J.Urol. 178(5):1883-1887 (2007)
to & Administration Adult Aged Agents Antineoplastic Carcinoma Cell Disease Disease-Free Female Follow-Up Humans Indoles Kidney Laboratories Male Method Middle Neoplasm Neoplasms Oral Outcome Progression Pyrroles Rate Renal Research Retrospective Single-Blind Staging States Studies Survival Treatment Tyrosine United administration dosage drug epidemiology methods mortality pathology response therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer
C. Kut, Gabhann F. Mac, and A. S. Popel Br.J.Cancer 97(7):978-985 (2007)
to A Assay Distribution Endothelial Enzyme-Linked Factor Growth Human Humans Immunosorbent Neoplasms Pharmacokinetics Prognosis Research Tissue Vascular blood cells diagnosis metabolism pathology protein by kanefendt on Feb 5, 2010, 11:28 AM
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The biology of epidermal growth factor receptor and its value as a prognostic/predictive factor
A. P. Dei Tos Int.J.Biol.Markers 22(1 Suppl 4):S3-S9 (2007)
to Antibodies Biological Epidermal Expression Factor Gene Growth Human Humans Immunohistochemistry Markers Monoclonal Neoplasms Neoplastic Prognosis Receptor Regulation Tyrosine analysis drug effects etiology identify pathology physiology response therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Surrogate biomarkers in evaluating response to anti-angiogenic agents: focus on sunitinib
S. E. Deprimo, and C. Bello Ann.Oncol (2007)
to Angiogenesis Biological Cells Endothelial Growth Humans Indoles Inhibitors Laboratories Markers Neoplasms Neovascularization Pathologic Proteins Pyrroles Research Tumor blood cells diagnosis drug effects metabolism methods pathology pharmacology protein response supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Molecular and cellular biomarkers for angiogenesis in clinical oncology
F. Bertolini, P. Mancuso, Y. Shaked, and R. S. Kerbel Drug Discov.Today 12(19-20):806-812 (2007)
to Angiogenesis Antigens Biological Cells Endothelial Humans Inhibitors Markers Microcirculation Neoplasms Neovascularization Pathologic Research Tumor blood cells diagnosis drug metabolism pathology pharmacology supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Angiogenesis: an organizing principle for drug discovery?
J. Folkman Nat.Rev.Drug Discov. 6(4):273-286 (2007)
to Agents Angiogenesis Animals Antineoplastic Blood Endothelium Humans Inhibitors Neoplasms Neovascularization Pathologic Physiologic Platelets RANGE Research drug effects genetics pathology pharmacology physiology therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy
J. M. Ebos, C. R. Lee, J. G. Christensen, A. J. Mutsaers, and R. S. Kerbel Proc.Natl.Acad.Sci.U.S.A 104(43):17069-17074 (2007)
to & A Administration Agents Angiogenesis Animals Antineoplastic Antitumor Assays Blood Cell Dose-Response Drug Endothelial Factor Female Growth Humans Hypoxia Indoles Inducing Line Mice Model Neoplasms Organ Outcome Placenta Pregnancy Proteins Pyrroles RANGE Receptor-2 Relationship Research Schedule Scid Specificity Treatment Tumor Tyrosine Vascular Xenograft administration blood dosage drug effects metabolism pathology pharmacology protein response therapy toxicity by kanefendt on Feb 5, 2010, 11:28 AM
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Molecular regulation of tumor angiogenesis: mechanisms and therapeutic implications
J. Harper, and M. A. Moses EXS (2006)
to & Angiogenesis Capillaries Human Humans Inhibitors Neoplasms Neovascularization Pathologic Research blood control drug metabolism pathology pharmacology prevention supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Measurement of plasma levels of vascular endothelial growth factor in prostate cancer patients: relationship with clinical stage, Gleason score, prostate volume, and serum prostate-specific antigen
J. L. Duque, K. R. Loughlin, R. M. Adam, P. Kantoff, E. Mazzucchi, and M. R. Freeman Clinics. 61(5):401-408 (2006)
to 80 A Adult Age Aged Antigen Biological Case-Control Distribution Endothelial Factor Growth Humans Immunoassay Male Markers Middle Neoplasm Neoplasms Nonparametric Organ Population Prognosis Prostate Prostate-Specific Prostatic Retrospective Size Staging Statistics Studies Tumor Vascular and blood methods over pathology physiology by kanefendt on Feb 5, 2010, 11:28 AM
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Regulation of cardiac growth and coronary angiogenesis by the Akt/PKB signaling pathway
I. Shiojima, and K. Walsh Genes Dev. 20(24):3347-3365 (2006)
to & Adaptation Animals Cardiac Cardiomegaly Cell Contraction Differentiation Diseases Failure Growth Heart Humans Hypertension Myocardial Myocytes Neovascularization Physiologic Physiological Proteins Proto-Oncogene Signal Sports Transduction c-akt cytology development embryology genetics growth metabolism pathology physiology physiopathology protein by kanefendt on Feb 5, 2010, 11:28 AM
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Isolation and enumeration of circulating endothelial cells by immunomagnetic isolation: proposal of a definition and a consensus protocol
A. Woywodt, A. D. Blann, T. Kirsch, U. Erdbruegger, N. Banzet, M. Haubitz, and F. gnat George J.Thromb.Haemost. 4(3):671-677 (2006)
to Antigens CD146 Cell Cells Chemistry Count Diseases Endothelial Humans Immunomagnetic Immunophenotyping Lectins Plant Reproducibility Results Separation Size Vascular analysis cells immunology methods of pathology by kanefendt on Feb 5, 2010, 11:28 AM
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The role of the VEGF-C/VEGFR-3 axis in cancer progression
J. L. Su, C. J. Yen, P. S. Chen, S. E. Chuang, C. C. Hong, I. H. Kuo, H. Y. Chen, M. C. Hung, and M. L. Kuo Br.J.Cancer 96(4):541-545 (2007)
to C Cells Disease Endothelial Factor Growth Human Humans Leukemia Lymphangiogenesis Lymphatic Neoplasms Progression Receptor-3 Research Vascular Vessels cells metabolism pathology physiopathology by kanefendt on Feb 5, 2010, 11:28 AM
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Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis
A. Y. Debrah, S. Mand, S. Specht, Y. Marfo-Debrekyei, L. Batsa, K. Pfarr, J. Larbi, B. Lawson, M. Taylor, O. Adjei, and A. Hoerauf PLoS.Pathog. 2(9):e92 (2006)
to & Adult Aged Animals C Data Doxycycline Elephantiasis Endothelial Factor Female Filarial Filaricides Growth Humans Hydrocele Intercellular Lymphatic Lymphedema Male Microfilaria Middle Molecular Outcome Parasitemia Peptides Plasma Proteins Receptor-3 Research Sequence Signaling System Testicular Testis Treatment Vascular Vessels Wolbachia and antagonists blood drug effects immunology inhibitors isolation parasitology pathology physiology protein purification therapeutic therapy ultrasonography use by kanefendt on Feb 5, 2010, 11:28 AM
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Vascular endothelial growth factor expression in monocytes from patients with primary antiphospholipid syndrome
M. J. Cuadrado, P. Buendia, F. Velasco, M. A. Aguirre, N. Barbarroja, L. A. Torres, M. Khamashta, and C. Lopez-Pedrera J.Thromb.Haemost. 4(11):2461-2469 (2006)
to & A Adolescent Adult Aged Antibodies Antiphospholipid Cells Cultured Endothelial Enzyme Expression Factor Female Gene Growth Human Humans Imidazoles Inhibitors Kinase Kinases MAP Male Middle Mitogen-Activated Monocytes Phenotype Protein Pyridines Receptor-1 Regulation Research Signaling Syndrome System Thromboplastin Thrombosis Tyrosine Vascular antagonists biosynthesis cells drug effects inhibitors metabolism p38 pathology pharmacology protein by kanefendt on Feb 5, 2010, 11:28 AM
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Identification of ligand-induced proteolytic cleavage and ectodomain shedding of VEGFR-1/FLT1 in leukemic cancer cells
N. Rahimi, T. E. Golde, and R. D. Meyer Cancer Res. 69(6):2607-2614 (2009)
to Amyloid B-Cell C Cell Cells Cytoplasm Diffuse Endothelial Factor Growth Humans Hypertension Kinase Large Ligands Lymphoma Membrane Necrosis Phosphorylation Precursor Protein Receptor-1 Research Secretases Signal Structure Tertiary Transduction Tyrosine Vascular biosynthesis cells enzymology metabolism pathology protein by kanefendt on Feb 5, 2010, 11:28 AM
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How well do angiogenesis inhibitors work? Biomarkers of response prove elusive
V. Brower J.Natl.Cancer Inst. 101(12):846-847 (2009)
to A Analysis Angiogenesis Animals Antibodies Benzenesulfonates Biological Cells Cytokines Disease-Free Endothelial Factor Growth Humans Indoles Inhibitors Markers Monoclonal Neoplasms Pyridines Pyrroles Survival Tumor Vascular blood drug effects metabolism mortality pathology pharmacology response supply therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Angiogenesis induced by hVEGF165 gene controlled by hypoxic response elements in rabbit ischemia myocardium
H. Dong, Q. Wang, Y. Zhang, B. Jiang, X. Xu, and Z. Zhang Exp.Biol.Med.Maywood. 234(12):1417-1424 (2009)
to 1 A Actins Animals Antigens Blood CD31 Dependovirus Elements Endothelial Expression Factor Gene Genetic Growth Heart Human Humans Hypoxia-Inducible Immunohistochemistry Ischemia Myocardial Myocardium Neovascularization Physiologic Rabbits Regulation Research Response Subunit Therapy Transduction Vascular Vessels alpha biosynthesis blood genetics pathology protein response therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Phase I dose escalation study of telatinib, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor 2 and 3, platelet-derived growth factor receptor beta, and c-Kit, in patients with advanced or metastatic solid tumors
F. A. Eskens, N. Steeghs, J. Verweij, J. L. Bloem, O. Christensen, Doorn L. van, J. Ouwerkerk, M. J. Jonge, J. W. Nortier, J. Kraetzschmar, P. Rajagopalan, and H. Gelderblom J.Clin.Oncol. 27(25):4169-4176 (2009)
to & A Administration Adolescent Adult Aged Angiogenesis Biological Contrast Dose Dose-Response Drug Endothelial Factor Factors Fatigue Female Growth Human Humans Hypertension Imaging Inhibitors Kinase Magnetic Male Markers Maximum Media Medical Metastasis Middle Neoplasm Neoplasms Oncology Oral Outcome Pharmacokinetics Plasma Platelet-Derived Protein Proteins Proto-Oncogene Pyridazines Pyridines Receptor Receptor-2 Receptor-3 Relationship Research Resonance Safety Schedule Time Tolerated Treatment Tumor Tyrosine Vascular Young administration adverse antagonists beta blood c-kit diagnostic dosage drug effects enzymology inhibitors methods pathology protein response supply therapy toxicity use by kanefendt on Feb 5, 2010, 11:28 AM
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High VEGFR-3-positive circulating lymphatic/vascular endothelial progenitor cell level is associated with poor prognosis in human small cell lung cancer
K. Bogos, F. Renyi-Vamos, J. Dobos, I. Kenessey, J. Tovari, J. Timar, J. Strausz, G. Ostoros, W. Klepetko, H. J. Ankersmit, G. Lang, M. A. Hoda, P. Nierlich, and B. Dome Clin.Cancer Res. 15(5):1741-1746 (2009)
to Adult Aged Antibodies Assay Bone C Capillaries Carcinoma Case-Control Cell Cells Cytometry Disease Endothelial Enzyme-Linked Factor Female Flow Follow-Up Growth Human Humans Immunosorbent Lung Lymphatic Male Marrow Metastasis Middle Neoplasms Population Prognosis Progression Rate Receptor-3 Research Small Stem Studies Survival Vascular Vessels blood cells metabolism pathology by kanefendt on Feb 5, 2010, 11:28 AM
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