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Key elements of bioanalytical method validation for macromolecules
M. Kelley, and B. DeSilva AAPS.J. 9(2):E156-E163 (2007)
to Antibodies Binding Chemistry Immunoassay Indicators Ligands Macromolecular Monoclonal Pharmaceutical Pharmacokinetics Preparations Reagents Reference Reproducibility Results Sensitivity Specificity Standards Substances analysis and metabolism methods of standards by kanefendt on Feb 5, 2010, 11:28 AM
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Appropriate calibration curve fitting in ligand binding assays
J. W. Findlay, and R. F. Dillard AAPS.J. 9(2):E260-E267 (2007)
to & Algorithms Analytical Binding Calibration Chemistry Dose-Response Drug Ligands Models Pharmaceutical Pharmacokinetics Preparations Protein RANGE Relationship Reproducibility Research Results Sensitivity Specificity Statistical analysis and data metabolism methods numerical of response statistics by kanefendt on Feb 5, 2010, 11:28 AM
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Vascular endothelial growth factor-D and its receptor VEGFR-3: two novel independent prognostic markers in gastric adenocarcinoma
S. Juttner, C. Wissmann, T. Jons, M. Vieth, J. Hertel, S. Gretschel, P. M. Schlag, W. Kemmner, and M. Hocker J.Clin.Oncol. 24(2):228-240 (2006)
to 80 Adenocarcinoma Adult Aged Antibodies C Cell Chemistry D Disease-Free Endothelial Factor Growth Humans Immunohistochemistry Laboratories Line Lymphatic Messenger Metastasis Middle Neoplasms Prognosis RNA Receptor-3 Research Stomach Survival Tumor Vascular analysis and blood genetics identify methods mortality over supply by kanefendt on Feb 5, 2010, 11:28 AM
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Measurement of plasma levels of vascular endothelial growth factor in prostate cancer patients: relationship with clinical stage, Gleason score, prostate volume, and serum prostate-specific antigen
J. L. Duque, K. R. Loughlin, R. M. Adam, P. Kantoff, E. Mazzucchi, and M. R. Freeman Clinics. 61(5):401-408 (2006)
to 80 A Adult Age Aged Antigen Biological Case-Control Distribution Endothelial Factor Growth Humans Immunoassay Male Markers Middle Neoplasm Neoplasms Nonparametric Organ Population Prognosis Prostate Prostate-Specific Prostatic Retrospective Size Staging Statistics Studies Tumor Vascular and blood methods over pathology physiology by kanefendt on Feb 5, 2010, 11:28 AM
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Quantitative bioanalytical methods validation and implementation: best practices for chromatographic and ligand binding assays
C. T. Viswanathan, S. Bansal, B. Booth, A. J. DeStefano, M. J. Rose, J. Sailstad, V. P. Shah, J. P. Skelly, P. G. Swann, and R. Weiner Pharm.Res. 24(10):1962-1973 (2007)
to & Administration Animals Artifacts Assay Binding Biological Body Calibration Chemistry Chromatography Control Documentation Drug Fluids Food Government Guidelines Humans Macromolecular Pharmaceutical Quality Radioligand Reference Regulation Reproducibility Research Results Species Specificity Stability Standards States Substances Technology Topic United and as jurisprudence legislation methods of standards by kanefendt on Feb 5, 2010, 11:28 AM
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Critical ligand binding reagent preparation/selection: when specificity depends on reagents
B. Rup, and D. O'Hara AAPS.J. 9(2):E148-E155 (2007)
to Antibodies Binding Chemistry Immunoassay Indicators Ligands Monoclonal Pharmaceutical Pharmacokinetics Preparations Reagents Reproducibility Research Results Safety Sensitivity Specificity and metabolism methods of standards by kanefendt on Feb 5, 2010, 11:28 AM
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Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis
A. Y. Debrah, S. Mand, S. Specht, Y. Marfo-Debrekyei, L. Batsa, K. Pfarr, J. Larbi, B. Lawson, M. Taylor, O. Adjei, and A. Hoerauf PLoS.Pathog. 2(9):e92 (2006)
to & Adult Aged Animals C Data Doxycycline Elephantiasis Endothelial Factor Female Filarial Filaricides Growth Humans Hydrocele Intercellular Lymphatic Lymphedema Male Microfilaria Middle Molecular Outcome Parasitemia Peptides Plasma Proteins Receptor-3 Research Sequence Signaling System Testicular Testis Treatment Vascular Vessels Wolbachia and antagonists blood drug effects immunology inhibitors isolation parasitology pathology physiology protein purification therapeutic therapy ultrasonography use by kanefendt on Feb 5, 2010, 11:28 AM
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Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma
M. Schmidinger, C. C. Zielinski, U. M. Vogl, A. Bojic, M. Bojic, C. Schukro, M. Ruhsam, M. Hejna, and H. Schmidinger J.Clin.Oncol. 26(32):5204-5212 (2008)
to 80 Aged Arteries Artery Benzenesulfonates Biological Carcinoma Cardiovascular Cell Coronary Disease Diseases Echocardiography Electrocardiography Estimate Factors Failure Female Heart Humans Hypertension Indoles Inhibitors Kaplan-Meiers Kidney Kinase Male Markers Metastasis Middle Neoplasm Neoplasms Outcome Prospective Protein Pyridines Pyrroles Renal Research Risk Studies Time Treatment Tyrosine adverse and blood chemically diagnosis drug effects enzymology induced methods mortality over pathology protein therapy toxicity by kanefendt on Feb 5, 2010, 11:28 AM
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Phase I dose escalation study of telatinib BAY 57-9352 in patients with advanced solid tumours
D. Strumberg, B. Schultheis, I. A. Adamietz, O. Christensen, M. Buechert, J. Kraetzschmar, P. Rajagopalan, M. Ludwig, A. Frost, S. Steinbild, M. E. Scheulen, and K. Mross Br.J.Cancer 99(10):1579-1585 (2008)
to & 80 Adult Aged Agents Angiogenesis Antineoplastic Carcinoma Dose Female Growth Humans Hypertension Imaging Inhibitors Magnetic Male Maximum Medical Middle Neoplasms Oncology Plasma Pyridazines Pyridines RANGE Resonance Tolerated Tyrosine administration and blood dosage drug over response therapy by kanefendt on Feb 5, 2010, 11:28 AM
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Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: a fluorescent in situ hybridization study
N. Personeni, S. Fieuws, H. Piessevaux, Hertogh G. De, Schutter J. De, B. Biesmans, Roock W. De, A. Capoen, M. biec Rychter, J. L. van Laethem, M. Peeters, Y. Humblet, Cutsem E. Van, and S. Tejpar Clin.Cancer Res. 14(18):5869-5876 (2008)
to 80 Adult Aged Antibodies Colorectal Disease-Free Dosage Female Fluorescence Gene Genes Genetic Humans Hybridization In Male Markers Middle Monoclonal Mutation Neoplasms Prognosis Research Situ Survival analysis and drug erbB-1 genetics over response therapeutic therapy use by kanefendt on Feb 5, 2010, 11:28 AM
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Vascular endothelial growth factor measured in platelet poor plasma allows optimal separation between cancer patients and volunteers: a key to study an angiogenic marker in vivo?
W. Wynendaele, R. Derua, M. F. Hoylaerts, A. Pawinski, E. Waelkens, E. A. Bruijn, R. Paridaens, W. Merlevede, and A. T. van Oosterom Ann.Oncol. 10(8):965-971 (1999)
to A Adult Aged Assay Biological Endothelial Enzyme-Linked Factor Factors Female Growth Humans Immunosorbent Lymphokines Male Markers Middle Neoplasms Neovascularization Nonparametric Pathologic RANGE Reference Research Sensitivity Specificity Statistics Tumor Values Vascular analysis and blood diagnosis methods by kanefendt on Feb 5, 2010, 11:28 AM
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Release of the angiogenic cytokine vascular endothelial growth factor VEGF from platelets: significance for VEGF measurements and cancer biology
R. E. Banks, M. A. Forbes, S. E. Kinsey, A. Stanley, E. Ingham, C. Walters, and P. J. Selby Br.J Cancer 77(6):956-964 (1998)
to A Acid Adult Aged Assay Biological Blood Bone Cells Citrates Collection Edetic Endothelial Enzyme-Linked Factor Factors Female Growth Healing Heparin Humans Immunohistochemistry Immunosorbent Indicators Lymphokines Male Markers Marrow Megakaryocytes Middle Platelets Reagents Reference Research Sensitivity Specificity Specimen Values Vascular Wound and biosynthesis blood cells cytology methods physiology by kanefendt on Feb 5, 2010, 11:28 AM
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Interference in immunoassay
C. Selby Ann.Clin.Biochem. (1999)
to Animals Humans Immunoassay Indicators Reagents Sensitivity Specificity and methods by kanefendt on Feb 5, 2010, 11:28 AM
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Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
D. J. Dumont, L. Jussila, J. Taipale, A. Lymboussaki, T. Mustonen, K. Pajusola, M. Breitman, and K. Alitalo Science 282(5390):946-949 (1998)
to Adult Animals Antigens Blood C CD31 Cardiovascular Cell Chemistry Development Embryo Embryonic Endothelial Endothelium Factor Factors Fetal Gene Growth Hematopoiesis Heterozygote Homozygote Hybridization Immunohistochemistry In Kinase Kinases Ligands Lymphatic Mammalian Mice Neovascularization Physiologic Protein-Tyrosine Receptor Receptor-3 Receptors Research Signal Situ Surface System Targeting Transduction Vascular Vessels analysis and blood embryology genetics physiology supply by kanefendt on Feb 5, 2010, 11:28 AM
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Validation of immunoassays for bioanalysis: a pharmaceutical industry perspective
J. W. Findlay, W. C. Smith, J. W. Lee, G. D. Nordblom, I. Das, B. S. DeSilva, M. N. Khan, and R. R. Bowsher J.Pharm.Biomed.Anal. 21(6):1249-1273 (2000)
to Algorithms Antibodies Calibration Control Disease Immunoassay Molecular Progression Quality Reproducibility Results Safety Sensitivity Specificity Weight analysis and metabolism methods of protein response standards by kanefendt on Feb 5, 2010, 11:28 AM
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Correlation of plasma and serum vascular endothelial growth factor levels with platelet count in colorectal cancer: clinical evidence of platelet scavenging?
M. L. George, S. A. Eccles, M. G. Tutton, A. M. Abulafi, and R. I. Swift Clin.Cancer Res. 6(8):3147-3152 (2000)
to 80 A Adult Aged Blood Colorectal Count Endothelial Factor Factors Female Growth Humans Lymphokines Male Middle Neoplasm Neoplasms Plasma Platelet Platelets Staging Vascular and blood cytology over pathology physiology supply surgery by kanefendt on Feb 5, 2010, 11:28 AM
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Bioanalytical method validation--a revisit with a decade of progress
V. P. Shah, K. K. Midha, J. W. Findlay, H. M. Hill, J. D. Hulse, I. J. McGilveray, G. McKay, K. J. Miller, R. N. Patnaik, M. L. Powell, A. Tonelli, C. T. Viswanathan, and A. Yacobi Pharm.Res. 17(12):1551-1557 (2000)
to Assay Availability Biological Equivalency Indicators Pharmaceutical Pharmacokinetics Preparations Reagents Reproducibility Research Results Therapeutic analysis and of by kanefendt on Feb 5, 2010, 11:28 AM
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Method dependence of interpretation of immunoassay results
U. H. Stenman, H. Alfthan, and U. Turpeinen Scand.J.Clin.Lab Invest Suppl (1991)
to & Animals Antibodies Antigens Binding Hormones Humans Immunoassay Neoplasm Peptides Protein Sensitivity Specificity analysis and data methods numerical standards statistics by kanefendt on Feb 5, 2010, 11:28 AM
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Calibration is the key to immunoassay but the ideal calibrator is unattainable
J. T. Whicher Scand.J.Clin.Lab Invest Suppl (1991)
to Antibodies Antigens Blood Calibration Humans Immunoassay Peptides Proteins Reference Sensitivity Specificity Standards analysis and blood immunology pathology protein standards by kanefendt on Feb 5, 2010, 11:28 AM
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The effects of common matrices for assay standards on performance of ültra sensitive" immunometric assays for TSH. Report of a joint WHO/IFCC collaborative study
R. E. Gaines-Das, H. Brettschneider, and A. F. Bristow Ann.Biol.Clin.Paris 49(10):522-527 (1991)
to Calibration Humans Hyperthyroidism Hypothyroidism Immunoassay Laboratories RANGE Sensitivity Specificity Thyrotropin and blood methods response standards by kanefendt on Feb 5, 2010, 11:28 AM
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